Cost-Effectiveness Analysis of Omalizumab for the Treatment of Severe Asthma in Japan and the Value of Responder Prediction Methods Based on a Multinational.

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Cost-Effectiveness Analysis of Omalizumab for the Treatment of Severe Asthma in Japan and the Value of Responder Prediction Methods Based on a Multinational Trial  Toshitaka Morishima, MD, Hiroshi Ikai, MD, PhD, Yuichi Imanaka, MD, MPH, PhD  Value in Health Regional Issues  Volume 2, Issue 1, Pages 29-36 (May 2013) DOI: 10.1016/j.vhri.2013.01.007 Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions

Fig. 1 Markov model structure for economic evaluation of omalizumab. Value in Health Regional Issues 2013 2, 29-36DOI: (10.1016/j.vhri.2013.01.007) Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions

Fig. 2 Tornado diagram summarizing one-way sensitivity analyses of the incremental cost-effectiveness ratio (cost per quality-adjusted life-year) of omalizumab plus standard therapy relative to standard therapy alone. RR indicates rate ratio for omalizumab plus standard therapy relative to standard therapy alone. Value in Health Regional Issues 2013 2, 29-36DOI: (10.1016/j.vhri.2013.01.007) Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions

Fig. 3 Cost-effectiveness acceptability curve. This graph illustrates the probability that a treatment strategy is cost-effective over a range of willingness-to-pay thresholds for an additional quality-adjusted life-year. Value in Health Regional Issues 2013 2, 29-36DOI: (10.1016/j.vhri.2013.01.007) Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Terms and Conditions