A diffuse infiltrating retinoblastoma

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Presentation transcript:

A diffuse infiltrating retinoblastoma Teaching NeuroImages Neurology Resident and Fellow Section © 2017 American Academy of Neurology

Vignette 4-year-old girl Painless heterochromia iridis Loss of visual acuity Funduscopic examination total retinal detachment vitreous hemorrhage. Friang et al © 2017 American Academy of Neurology

 *  Imaging Friang et al Imaging. Ultrasonography and axial T2-weighted MR imaging showing a total retinal detachment (arrows) with a coarse nodular calcification on a thickened retinal fold (arrowhead) and a subretinal hemorrhage (asterisk) © 2017 American Academy of Neurology Friang et al

Imaging Histology showing a diffuse infiltrating retinoblastoma. Friang et al © 2017 American Academy of Neurology

A diffuse infiltrating retinoblastoma This entity is rare It must be suspected in case of a calcified retinal detachment in young children Enucleation is the diagnosis of choice 1. Brisse HJ, Lumbroso L, Fréneaux PC, et al. Sonographic, CT, and MR imaging findings in diffuse infiltrative retinoblastoma: report of two cases with histologic comparison. AJNR Am J Neuroradiol. 2001;22:499–504. 2. Shields CL, Ghassemi F, Tuncer S, Thangappan A, Shields JA. Clinical spectrum of diffuse infiltrating retinoblastoma in 34 consecutive eyes. Ophthalmology. 2008;115:2253–2258. © 2017 American Academy of Neurology Friang et al