Joseph F. Sabik, MD, Gabriel Olivares, MD, Sajjad Raza, MD, Bruce W

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Presentation transcript:

Does grafting coronary arteries with only moderate stenosis affect long-term mortality? Joseph F. Sabik, MD, Gabriel Olivares, MD, Sajjad Raza, MD, Bruce W. Lytle, MD, Penny L. Houghtaling, MS, Eugene H. Blackstone, MD The Journal of Thoracic and Cardiovascular Surgery Volume 151, Issue 3, Pages 806-811.e3 (March 2016) DOI: 10.1016/j.jtcvs.2015.10.021 Copyright © 2016 Terms and Conditions

Figure 1 Unadjusted long-term survival in patients undergoing coronary artery bypass grafting (CABG) with 1 moderately stenosed artery (n = 8531). Curves are Kaplan-Meier estimates with associated 68% confidence limits (vertical bars). A, Stratified by grafted versus nongrafted artery. B, Stratified by internal thoracic artery (ITA) grafting versus saphenous vein (SV) grafting versus nongrafting of artery. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 806-811.e3DOI: (10.1016/j.jtcvs.2015.10.021) Copyright © 2016 Terms and Conditions

Figure 2 Adjusted long-term survival in patients undergoing coronary artery bypass grafting (CABG) with 1 moderately stenosed coronary artery. Solid lines are parametric estimates enclosed within 68% dashed confidence limits. Panel (A) is a nomogram of the multivariable equation in Table E1 and panel (B) is a nomogram of the multivariable equation in Table E2 for a patient with the following characteristics: age = 60 years, body mass index = 28 kg·m−2, weight = 80 kg, no previous stroke, no heart failure, no peripheral vascular disease, no history of smoking, no diabetes, no prior myocardial infarction, New York Heart Association functional class II, triglycerides = 180 mg·dL−1, number of internal thoracic artery grafts to vessel with severe stenosis (≥70%) = 1, number of diseased coronary systems = 3. A, Stratified by grafting versus nongrafting of artery. B, Stratified by internal thoracic artery (ITA) grafting versus saphenous vein grafting (SVG) versus nongrafting of artery. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 806-811.e3DOI: (10.1016/j.jtcvs.2015.10.021) Copyright © 2016 Terms and Conditions

Figure E1 Survival advantage of internal thoracic artery (ITA) grafting of a moderately stenosed non–left anterior descending coronary artery (LAD) after ITA grafting of a severely stenosed LAD. Format is as in Figure 1. SVG, Saphenous vein graft; CABG, coronary artery bypass grafting. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 806-811.e3DOI: (10.1016/j.jtcvs.2015.10.021) Copyright © 2016 Terms and Conditions

Survival after ITA versus SV grafting versus no grafting of moderately stenosed coronary arteries. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 806-811.e3DOI: (10.1016/j.jtcvs.2015.10.021) Copyright © 2016 Terms and Conditions