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Volume 58, Issue 3, Pages 1211-1218 (September 2000) Pulse pressure and isolated systolic hypertension: Association with microalbuminuria Massimo Cirillo, Davide Stellato, Martino Laurenzi, Walter Panarelli, Alberto Zanchetti, Natale G. De Santo Kidney International Volume 58, Issue 3, Pages 1211-1218 (September 2000) DOI: 10.1046/j.1523-1755.2000.00276.x Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 1 Percent prevalence of isolated systolic hypertension by age in men (▪) and women (□). Isolated systolic hypertension was defined as systolic pressure ≥140 mm Hg in subjects not on treatment with antihypertensive drug(s) and with a diastolic pressure <90 mm Hg. The number of people represented in the age ranges are 103 to 137 men and 145 to 186 women. Kidney International 2000 58, 1211-1218DOI: (10.1046/j.1523-1755.2000.00276.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 2 Mean values of urinary albumin excretion (A) and of creatinine clearance (B) plotted over the mean of pulse pressure in quintiles of pulse pressure for men (•) and women (○).P values are given by a test for linearity across quintiles (ANOVA). In panel A, P = 0.007 for men and P < 0.001 for women; in panel B, P = 0.234 for men and P = 0.269 for women. The number of persons per quintile are 131 to 139 men and 173 to 179 women. Kidney International 2000 58, 1211-1218DOI: (10.1046/j.1523-1755.2000.00276.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 3 Percent prevalence of microalbuminuria (urinary albumin excretion 20 to 199 μg/min) plotted over the mean of pulse pressure in quintiles of pulse pressure for men (•) and women (○).P < 0.001 for both men and women, by a test for linearity across quintiles (chi-square analysis). The number of persons per quintile are 131 to 139 men and 173 to 179 women. Kidney International 2000 58, 1211-1218DOI: (10.1046/j.1523-1755.2000.00276.x) Copyright © 2000 International Society of Nephrology Terms and Conditions