G. Blumenkrantz, B. S. , R. Stahl, M. D. , J. Carballido-Gamio, Ph. D

Slides:

Advertisements

Similar presentations

Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the Multicenter Osteoarthritis Study J.J. Stefanik,

Advertisements

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative M. Hakky, M. Jarraya,

T1ρ relaxation time of the meniscus and its relationship with T1ρ of adjacent cartilage in knees with acute ACL injuries at 3T R.I. Bolbos, Ph.D., T.M.

Cross-sectional and longitudinal study of the impact of posterior meniscus horn lesions on adjacent cartilage composition, patient-reported outcomes and.

Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study F.W. Roemer, T. Neogi,

Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the Multicenter Osteoarthritis Study J.J. Stefanik,

T1ρ and T2 relaxation times predict progression of knee osteoarthritis

Osteoarthritis year 2013 in review: imaging

Trabecular bone structure and spatial differences in articular cartilage MR relaxation times in individuals with posterior horn medial meniscal tears

Evaluation of cartilage matrix disorders by T2 relaxation time in patients with hip dysplasia T. Nishii, M.D., H. Tanaka, M.D., N. Sugano, M.D., T. Sakai,

Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort W. Wirth, M.S., M.-P. Hellio.

Imaging of non-osteochondral tissues in osteoarthritis

7th International Workshop on Osteoarthritis Imaging report: “imaging in OA – now is the time to move ahead” A. Guermazi, F. Eckstein, D. Hunter, F.

Patient-specific chondrolabral contact mechanics in patients with acetabular dysplasia following treatment with peri-acetabular osteotomy C.L. Abraham,

Evaluation of cartilage repair in the distal femur after autologous chondrocyte transplantation using T2 relaxation time and dGEMRIC J.E. Kurkijärvi,

A novel fast knee cartilage segmentation technique for T2 measurements at MR imaging – data from the Osteoarthritis Initiative C. Stehling, T. Baum,

The acutely ACL injured knee assessed by MRI: changes in joint fluid, bone marrow lesions, and cartilage during the first year R.B. Frobell, P.T., Ph.D.,

Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI.

Cancellous bone differences between knees with early, definite and advanced joint space loss; a comparative quantitative macroradiographic study Elizabeth.

M. C. Gallo, C. Wyatt, V. Pedoia, D. Kumar, S. Lee, L. Nardo, T. M

Bilateral cartilage T2 mapping 9 years after Mega-OATS implantation at the knee: a quantitative 3T MRI study P.M. Jungmann, P.U. Brucker, T. Baum, T.M.

Quantitatively-measured bone marrow lesions in the patellofemoral joint: distribution and association with pain C. Ratzlaff, R. Russell, J. Duryea Osteoarthritis.

Differences between X-ray and MRI-determined knee cartilage thickness in weight- bearing and non-weight-bearing conditions M. Marsh, R.B. Souza, B.T.

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

Demographic and biomechanical factors related to structural progression of hip osteoarthritis over 18 months D. Kumar, C. Wyatt, N. Okazaki, K. Chiba,

Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA – data from the OA initiative

Radiographic and MRI assessment in osteoarthritis efficacy studies and anti-nerve growth factor programs: Characteristics and differences A. Guermazi,

Change in bone area does not correlate with cartilage loss over 12 months in individuals with knee OA: Data from the osteoarthritis initiative M.A. Bowes,

Differences in trabecular bone texture between knees with and without radiographic osteoarthritis detected by fractal methods P. Podsiadlo, Ph.D., L.

B. C. Fleming, H. L. Oksendahl, W. A. Mehan, R. Portnoy, P. D

DGEMRIC as a tool for measuring changes in cartilage quality following high tibial osteotomy: a feasibility study M. Rutgers, L.W. Bartels, A.I. Tsuchida,

A. A. Qazi, M. Sc. , J. Folkesson, M. Sc. , P. C. Pettersen, M. D. , M

Subregional femorotibial cartilage morphology in women – comparison between healthy controls and participants with different grades of radiographic knee.

Is increased joint loading detrimental to obese patients with knee osteoarthritis? A secondary data analysis from a randomized trial M. Henriksen, D.J.

Osteoarthritis may not be a one-way-road of cartilage loss – comparison of spatial patterns of cartilage change between osteoarthritic and healthy knees

D. Hayashi, F.W. Roemer, A. Guermazi Osteoarthritis and Cartilage

Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3years –

Pre-radiographic osteoarthritic changes are highly prevalent in the medial patella and medial posterior femur in older persons: Framingham OA study D.

The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period M.D. Crema, A.

Bone marrow lesions and joint effusion are strongly and independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis.

Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative W. Wirth, J. Duryea,

Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the osteoarthritis initiative S. Maschek,

The lateral wedged insole with subtalar strapping significantly reduces dynamic knee load in the medial compartment Y. Kuroyanagi, M.D., T. Nagura, M.D.,

Role of physical activity in cartilage damage progression of subjects with baseline full- thickness cartilage defects in medial tibiofemoral compartment:

Structural changes in the knee during weight loss maintenance after a significant weight loss in obese patients with osteoarthritis: a report of secondary.

Comments on Beattie et al

Magnetic resonance imaging (MRI)-defined cartilage degeneration and joint pain are associated with poor physical function in knee osteoarthritis – the.

Volumetric bone mineral density of the tibia is not increased in subjects with radiographic knee osteoarthritis M. Abdin-Mohamed, M.B.B.S., M.R.C.P.,

Progression of cartilage damage and meniscal pathology over 30 months is associated with an increase in radiographic tibiofemoral joint space narrowing.

Medial meniscus posterior horn zones show differing responses to static loading in subjects with knee osteoarthritis compared to controls N.E. Calixto,

MRI-derived T2 relaxation times and cartilage morphometry of the tibio-femoral joint in subjects with and without osteoarthritis during a 1-year follow-up

X. Li, Ph. D. , C. Benjamin Ma, M. D. , T. M. Link, M. D. , D. -D

Association of cartilage defects, and other MRI findings with pain and function in individuals with mild–moderate radiographic hip osteoarthritis and.

Elevated cartilage T2 and increased severity of cartilage defects at baseline are associated with the development of knee pain over 7 years G.B. Joseph,

Surface roughness and thickness analysis of contrast-enhanced articular cartilage using mesh parameterization T. Maerz, M.D. Newton, H.W.T. Matthew,

A pilot study of the reproducibility and validity of measuring knee subchondral bone density in the tibia D. Dore, BBiotech.(Hons.), C. Ding, M.D., G.

Region of interest analysis: by selecting regions with denuded areas can we detect greater amounts of change? D.J. Hunter, L. Li, Y.Q. Zhang, S. Totterman,

Optimization of the fixed-flexion knee radiograph

Longitudinal evaluation of T1ρ and T2 spatial distribution in osteoarthritic and healthy medial knee cartilage J. Schooler, D. Kumar, L. Nardo, C. McCulloch,

Osteoarthritis year 2012 in review: biology

Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen.

R. B. Souza, C. Stehling, B. T. Wyman, M. -P. Hellio Le Graverand, X

M. Hudelmaier, W. Wirth Osteoarthritis and Cartilage

The acutely ACL injured knee assessed by MRI: are large volume traumatic bone marrow lesions a sign of severe compression injury? R.B. Frobell, P.T.,

Osteoarthritis and Cartilage

B. C. Fleming, H. L. Oksendahl, W. A. Mehan, R. Portnoy, P. D

A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee Gabrielle Blumenkrantz,

Longitudinal analysis of cartilage T2 relaxation times and joint degeneration in African American and Caucasian American women over an observation period.

Association between bone marrow lesions detected by magnetic resonance imaging and knee pain in community residents in Korea I.J. Kim, D.H. Kim, J.Y.

Presentation transcript:

The feasibility of characterizing the spatial distribution of cartilage T2 using texture analysis G. Blumenkrantz, B.S., R. Stahl, M.D., J. Carballido-Gamio, Ph.D., S. Zhao, Ph.D., Y. Lu, Ph.D., T. Munoz, M.D., M.-P. Hellio Le Graverand-Gastineau, M.D., Ph.D., S.K. Jain, M.D., T.M. Link, M.D., S. Majumdar, Ph.D. Osteoarthritis and Cartilage Volume 16, Issue 5, Pages 584-590 (May 2008) DOI: 10.1016/j.joca.2007.10.019 Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Representative T2 colormaps overlayed on T2-weighted images of an advanced OA patient (cartilage WORMS=5) (left), a mild OA patient (cartilage WORMS=1) (center), and a control subject (right). The entropy and ASM of cartilage T2 for the OA patients and control subject are listed in the table. The OA patients both have greater entropy and lower ASM than the control subject. Osteoarthritis and Cartilage 2008 16, 584-590DOI: (10.1016/j.joca.2007.10.019) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Entropy (top row) of cartilage T2 is greater in OA patients than in controls in all compartments combined, the lateral femur, and the medial tibia at 0° (top left) and 90° (top left). ASM (bottom row) of cartilage T2 greater in controls than in OA patients in all compartments combined, the lateral femur, and the medial tibia at 0° (bottom left) and 90° (bottom right). The ‘’ indicates a significant difference (P<0.05) between OA patients and controls. The ‘’ indicates P<0.10. Osteoarthritis and Cartilage 2008 16, 584-590DOI: (10.1016/j.joca.2007.10.019) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Increased (P<0.10) cartilage T2 ASM was evident in OA patients from baseline to 9 months. Decreased (P<0.10) cartilage T2 entropy was evident in OA patients from baseline to 9 months. Osteoarthritis and Cartilage 2008 16, 584-590DOI: (10.1016/j.joca.2007.10.019) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Sagittal T2-weighted FSE images (top row) and cartilage T2 maps overlayed on T2-weighted FSE images (bottom row) of an OA patient at baseline and 9 months. At baseline, the cartilage signal at the posterior lateral tibia (arrow) is inhomogeneous (a) and at 9 months, an extensive cartilage defect with a more homogeneous signal has developed in the same area (arrow in [b]). An extensive adjacent bone marrow edema pattern is also evident. Visually, there is a decrease in the heterogeneity of T2 values from baseline to follow-up. Osteoarthritis and Cartilage 2008 16, 584-590DOI: (10.1016/j.joca.2007.10.019) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions