Rethinking Cocaine-Associated Chest Pain and Acute Coronary Syndromes

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Presentation transcript:

Rethinking Cocaine-Associated Chest Pain and Acute Coronary Syndromes Jonathan B. Finkel, MD, Gregary D. Marhefka, MD Mayo Clinic Proceedings Volume 86, Issue 12, Pages 1198-1207 (December 2011) DOI: 10.4065/mcp.2011.0338 Copyright © 2011 Mayo Foundation for Medical Education and Research Terms and Conditions

FIGURE 1 Cocaine's pathologic cardiovascular effects that lead to chest pain. BP = blood pressure; HR = heart rate; NO = nitric oxide; PF4: platelet factor 4; SMC = smooth muscle cell; TGB = thromboglobulin B. Mayo Clinic Proceedings 2011 86, 1198-1207DOI: (10.4065/mcp.2011.0338) Copyright © 2011 Mayo Foundation for Medical Education and Research Terms and Conditions

FIGURE 2 Evaluation and management of cocaine-associated chest pain. ASA = aspirin; CCB = calcium channel blocker; ECG = electrocardiography; HR = heart rate; NTG = nitroglycerin; SBP = systolic blood pressure. Mayo Clinic Proceedings 2011 86, 1198-1207DOI: (10.4065/mcp.2011.0338) Copyright © 2011 Mayo Foundation for Medical Education and Research Terms and Conditions