Advances in Alport Syndrome

Alport Syndrome (AS)

AS Is Often Undiagnosed or Misdiagnosed

Genetic Mutations in AS

Type IV Collagen Networks

AS Prevalence

Alport Nephropathy Early and Accurate Diagnosis Is Critical

Early Diagnosis and Management of AS Can Improve Prognosis

Current Approaches for AS

Early Treatment With ACEI Preserves Renal Function in Children With CKD

CKiD Study -- Proteinuria is Major Risk Factor

Chronic Inflammation Plays a Central Role in CKD Progression

Bardoxolone Methyl Targets the NF-κB Cascade

Bardoxolone Methyl in Alport Syndrome CARDINAL Phase 2/3 Study Efficacy Results

Bardoxolone Methyl in Alport Syndrome CARDINAL Phase 2/3 Study Safety Results

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