Terminology relating to methods for the determination of susceptibility of bacteria to antimicrobial agents Clinical Microbiology and Infection Volume.

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Terminology relating to methods for the determination of susceptibility of bacteria to antimicrobial agents Clinical Microbiology and Infection Volume 6, Issue 9, Pages 503-508 (September 2000) DOI: 10.1046/j.1469-0691.2000.00149.x Copyright © 2000 Terms and Conditions

Figure 1 Hypothetical distribution of MICs among strains of bacteria isolated from infected patients, classified as clinically susceptible (fully or borderline), intermediate or resistant, and microbiologically susceptible or low-level, moderately or high-level resistant. Clinical Microbiology and Infection 2000 6, 503-508DOI: (10.1046/j.1469-0691.2000.00149.x) Copyright © 2000 Terms and Conditions

Figure 2 Interpretation of an isobologram for two antibiotics A and B in a checkerboard titration. Clinical Microbiology and Infection 2000 6, 503-508DOI: (10.1046/j.1469-0691.2000.00149.x) Copyright © 2000 Terms and Conditions

Figure 3 Hypothetical time-kill curves for two antibiotics A and B acting on a bacterial culture alone and in combination demonstrating synergism (the difference in Δ log CFU/h for the combination being ≥ 2-fold that of the most active component). Clinical Microbiology and Infection 2000 6, 503-508DOI: (10.1046/j.1469-0691.2000.00149.x) Copyright © 2000 Terms and Conditions