Cockroach allergens: Coping with challenging complexity

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Presentation transcript:

Cockroach allergens: Coping with challenging complexity Jörg Kleine-Tebbe, MD, Robert G. Hamilton, PhD, Richard E. Goodman, PhD Journal of Allergy and Clinical Immunology Volume 143, Issue 4, Pages 1342-1344 (April 2019) DOI: 10.1016/j.jaci.2019.01.028 Copyright © 2019 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 German cockroach allergen extracts display variable potencies (represented by a wavy line). Heterogeneous IgE repertoires (upper left panel, with individual allergen-specific IgE levels to single cockroach allergens) and complex allergen composition (lower left panel) contribute to the complexity. Journal of Allergy and Clinical Immunology 2019 143, 1342-1344DOI: (10.1016/j.jaci.2019.01.028) Copyright © 2019 American Academy of Allergy, Asthma & Immunology Terms and Conditions