Double-Unit Cord Blood Transplantation after Myeloablative Conditioning for Patients with Hematologic Malignancies: A Multicenter Phase II Study in Japan 

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Presentation transcript:

Double-Unit Cord Blood Transplantation after Myeloablative Conditioning for Patients with Hematologic Malignancies: A Multicenter Phase II Study in Japan  Shunro Kai, Atsushi Wake, Masaya Okada, Mio Kurata, Yoshiko Atsuta, Jun Ishikawa, Hirohisa Nakamae, Nobuyuki Aotsuka, Masaharu Kasai, Mahito Misawa, Shuichi Taniguchi, Shunichi Kato  Biology of Blood and Marrow Transplantation  Volume 19, Issue 5, Pages 812-819 (May 2013) DOI: 10.1016/j.bbmt.2013.02.011 Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Kaplan-Meier analysis of EFS in patients with dCBT after myeloablative conditioning (A) and according to disease status (B). Patients with standard risk had significantly better posttransplantation survival than those with advanced risk (P = .023, log-rank test). Biology of Blood and Marrow Transplantation 2013 19, 812-819DOI: (10.1016/j.bbmt.2013.02.011) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Cumulative incidence of neutrophil engraftment after myeloablative conditioning and subsequent dCBT. Biology of Blood and Marrow Transplantation 2013 19, 812-819DOI: (10.1016/j.bbmt.2013.02.011) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Cumulative incidence of grade II-IV aGVHD (A), cGVHD (B), relapse (C), and TRM (D). Biology of Blood and Marrow Transplantation 2013 19, 812-819DOI: (10.1016/j.bbmt.2013.02.011) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions