Fluticasone propionate powder administered through Diskhaler versus triamcinolone acetonide aerosol administered through metered-dose inhaler in patients.

Slides:

Advertisements

Similar presentations

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

Advertisements

W.Travis Cain, MDa, Greg Cable, PhDb, John J. Oppenheimer, MDc

Comparison of adjustable- and fixed-dose budesonide/formoterol pressurized metered- dose inhaler and fixed-dose fluticasone propionate/salmeterol dry powder.

Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome Paul Steinberg, MDa, Bruce E.

Salmeterol resolves airway obstruction but does not possess anti-eosinophil efficacy in newly diagnosed asthma: A randomized, double-blind, parallel group.

Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M

Zafirlukast improves asthma symptoms and quality of life in patients with moderate reversible airflow obstruction Robert A. Nathan, MDa, Jonathan A.

Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with.

A randomized, vehicle-controlled trial of tacrolimus ointment for treatment of atopic dermatitis in children Mark Boguniewicz, MDa, Virginia C. Fiedler,

Richard L. ZuWallack, MD a,b, James P

Fluticasone furoate nasal spray: A single treatment option for the symptoms of seasonal allergic rhinitis Harold B. Kaiser, MD, Robert M. Naclerio, MD,

Protective effect of inhaled budesonide against unlimited airway narrowing to methacholine in atopic patients with asthma Patrick Booms, MSca, David.

Enhanced synergy between fluticasone propionate and salmeterol inhaled from a single inhaler versus separate inhalers Harold S. Nelson, MDa, Kenneth.

Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis Paul H. Ratner,

Badrul A. Chowdhury, MD, PhD

Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma Annika Wallin, PhDa, Malcolm Sue-Chu, PhDb, Leif Bjermer,

Comparison of the efficacy of budesonide and fluticasone propionate aqueous nasal spray for once daily treatment of perennial allergic rhinitis James.

Harold B. Kaiser, MDa, Steven R. Findlay, MD†, John W

Mark T. S. Chan, MDa, Donald Y. M. Leung, MD, PhDb, Stanley J

Comparative Analysis of Persistence to Treatment among Patients with Asthma or COPD Receiving AirFluSal Forspiro or Seretide Diskus Salmeterol/Fluticasone.

Elinor Simons, MDa, William M

Low-dose fluticasone propionate compared with montelukast for first-line treatment of persistent asthma: A randomized clinical trial William Busse, MDa,

Inhaled fluticasone propionate delivered by means of two different multidose powder inhalers is effective and safe in a large pediatric population with.

Low-dose levalbuterol in children with asthma: Safety and efficacy in comparison with placebo and racemic albuterol Henry Milgrom, MDa, David P. Skoner,

Side effects of inhaled corticosteroids

Michael Mellon, MD Journal of Allergy and Clinical Immunology

Efficacy and safety of budesonide inhalation suspension (Pulmicort Respules) in young children with inhaled steroid–dependent, persistent asthma Gail.

Allergic rhinoconjunctivitis caused by Harmonia axyridis (Asian lady beetle, Japanese lady beetle, or lady bug) John A. Yarbrough, MDa, Jack L. Armstrong,

Increased sensitivity to bradykinin among African Americans

H.William Kelly, PharmD Journal of Allergy and Clinical Immunology

Paul M. O’Byrne, MB, FRCPI, FRCP(C)a, Soren Pedersen, MD, PhDb

A dose-ranging study of the efficacy and safety of azelastine nasal spray in the treatment of seasonal allergic rhinitis with an acute model John M.

Physician-targeted program on inhaled therapy for childhood asthma

News & Notes Journal of Allergy and Clinical Immunology

Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype Atsuko Takao, MDa, Terufumi Shimoda, MDa, Shigeru Kohno, MDa, Sadahiro.

James P. Kemp, MDa, David A. Cook, MDb, Gary A

Salmeterol and fluticasone propionate combined in a new powder inhalation device for the treatment of asthma: A randomized, double-blind, placebo-controlled.

Inhaled mometasone furoate reduces oral prednisone requirements while improving respiratory function and health-related quality of life in patients with.

M1a/M1b esophageal carcinoma: Clinical relevance

Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma William.

Salmeterol resolves airway obstruction but does not possess anti-eosinophil efficacy in newly diagnosed asthma: A randomized, double-blind, parallel group.

Frederick L. Grover, MDa, b, David J

Jack M. Becker, MDa, Anjali Arora, MDb, Richard J

Clinical need for a nebulized corticosteroid

Thomas B. Casale, MDa, I. Leonard Bernstein, MDb, William W

A comparison of multiple doses of fluticasone propionate and beclomethasone dipropionate in subjects with persistent asthma Gordon D. Raphael, MDa, Robert.

News & Notes Journal of Allergy and Clinical Immunology

The effects of triamcinolone acetonide aqueous nasal spray on adrenocortical function in children with allergic rhinitis Anjuli S. Nayak, MDa, Mark H.

Fluticasone propionate powder: Oral corticosteroid–sparing effect and improved lung function and quality of life in patients with severe chronic asthma

A placebo- and active-controlled randomized trial of prophylactic treatment of seasonal allergic rhinitis with mometasone furoate aqueous nasal spray

Low-dose inhaled fluticasone propionate versus oral zafirlukast in the treatment of persistent asthma Eugene R. Bleecker, MDa, Michael J. Welch, MDb,

Omalizumab improves asthma-related quality of life in patients with severe allergic asthma Albert Finn, MDa, Gary Gross, MDb, Julius van Bavel, MDc,

Comparison of adjustable- and fixed-dose budesonide/formoterol pressurized metered- dose inhaler and fixed-dose fluticasone propionate/salmeterol dry powder.

Bruce G. Bender, PhD, Alex Pedan, PhD, Laleh T. Varasteh, RPh, MSF

Steroid-sparing effects of fluticasone propionate 100 μg and salmeterol 50 μg administered twice daily in a single product in patients previously controlled.

Preparing patients and health professionals for the transition to chlorofluorocarbon-free inhalers: The British perspective Helen Donohoe, MSc (Econ)

Mometasone furoate administered once daily is as effective as twice-daily administration for treatment of mild-to-moderate persistent asthma James P.

Studies on the relationship between the level of specific IgE antibodies and the clinical expression of allergy: I. Definition of levels distinguishing.

Sami T. Remes, MD, MPHa,b, Jose A. Castro-Rodriguez, MDa, Catharine J

Anaphylaxis after initial ingestion of rambutan, a tropical fruit

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

Further studies on the chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy Diane J. Pincus, MD, Teresa R. Humeston,

Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M

Primary repair is superior to initial palliation in children with atrioventricular septal defect and tetralogy of fallot Hani K. Najm, MDa, Glen S. Van.

National trends in asthma visits and asthma pharmacotherapy,

Larry C. Borish, MDa, Harold S

Statistical issues in clinical trials that involve the double-blind, placebo-controlled food challenge Vernon M. Chinchilli, PhD, Laura Fisher, MD, Timothy.

Asthma symptoms and airway hyperresponsiveness are lower during treatment with nedocromil sodium than during treatment with regular inhaled albuterol

News & Notes Journal of Allergy and Clinical Immunology

Clinical relevance of inhaled corticosteroids and HPA axis suppression

Presentation transcript:

Fluticasone propionate powder administered through Diskhaler versus triamcinolone acetonide aerosol administered through metered-dose inhaler in patients with persistent asthma John J. Condemi, MDa, Paul Chervinsky, MDb, Marc F. Goldstein, MDc, Linda B. Ford, MDd, William E. Berger, MDe, Garrison H. Ayars, MDf, Paula R. Rogenes, PhDg, Lisa Edwards, PhDg, Pamela J. Pepsin, RN, BAg Journal of Allergy and Clinical Immunology Volume 100, Issue 4, Pages 467-474 (October 1997) DOI: 10.1016/S0091-6749(97)70137-4 Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 1 Mean change from baseline in morning predose FEV1 at end point (*p < 0.05 vs placebo, †p < 0.05 FP vs TAA). BID, Twice daily; QID; four times daily. End-point analysis = final estimable measurement for all patients including those who failed to complete the entire study. Journal of Allergy and Clinical Immunology 1997 100, 467-474DOI: (10.1016/S0091-6749(97)70137-4) Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 2 Mean change from baseline in morning predose PEF (*p < 0.05 vs placebo, †p < 0.05 FP vs TAA). BID, Twice daily; QID, four times daily. End-point analysis = final estimable measurement for all patients including those who failed to complete the entire study. Journal of Allergy and Clinical Immunology 1997 100, 467-474DOI: (10.1016/S0091-6749(97)70137-4) Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 3 Probability of remaining in the study according to Kaplan-Meier Survival Curve (p < 0.001 vs placebo; p = 0.06, FP vs TAA). BID, Twice daily; QID, four times daily. Journal of Allergy and Clinical Immunology 1997 100, 467-474DOI: (10.1016/S0091-6749(97)70137-4) Copyright © 1997 Mosby, Inc. Terms and Conditions