Pulmonary Angiomyolipoma

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Pulmonary Angiomyolipoma Bertrand Marcheix, MD, Laurent Brouchet, MD, Yoan Lamarche, MD, Claire Renaud, MD, Anne Gomez-Brouchet, MD, Lucy Hollington, MD, Valérie Chabbert, MD, John Berjaud, MD, Marcel Dahan, MD The Annals of Thoracic Surgery Volume 82, Issue 4, Pages 1504-1506 (October 2006) DOI: 10.1016/j.athoracsur.2006.02.053 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 (a) Anteroposterior chest roentgenogram demonstrating a nodular opacity in the inferior region without any calcifications (arrow). Computed tomographic scan of the axial view with (b) parenchymal settings and (c–e) mediastinal settings. (e) Magnified view 1 minute after the injection of iodine contrast. The lesion (28 × 23 mm) appears composite and heterogeneous before and after the contrast media injection. Fatty densities (−40 Hounsfield Unit) were measured in the macronodule. The other component showed strong enhancement 1 minute after the injection. (f) coronal, (g) sagittal, and (h) axial positron emission tomographic–computed tomographic scan showing a solitary focus of intense tracer location in the right lower lobe. The Annals of Thoracic Surgery 2006 82, 1504-1506DOI: (10.1016/j.athoracsur.2006.02.053) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 (a) Pulmonary tumor, which is well-delineated with a thin fibrous pseudocapsule. (Hematoxylin and eosin; ×20.) (b) Three components: mature adipose tissue, mature smooth muscle arranged in short fascicles, and medium caliber thick-walled blood vessels. No appreciable mitotic activity. No necrosis. (Hematoxylin and eosin; ×150.) (c) Identical immunopositivity for H Caldesmone and Desmine on tumor cells. (Hematoxylin and eosin; ×150.) (D) Focal staining of tumor cells with the HMB45 antibody. (Hematoxylin and eosin; ×150.) The Annals of Thoracic Surgery 2006 82, 1504-1506DOI: (10.1016/j.athoracsur.2006.02.053) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions