Usefulness of a quantitative real-time PCR assay using serum samples to discriminate between inactive, serologically positive and active human brucellosis

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Presentation transcript:

Usefulness of a quantitative real-time PCR assay using serum samples to discriminate between inactive, serologically positive and active human brucellosis M.I. Queipo-Ortuño, J.D. Colmenero, M.J. Bravo, M.A. García-Ordoñez, P. Morata Clinical Microbiology and Infection Volume 14, Issue 12, Pages 1128-1134 (December 2008) DOI: 10.1111/j.1469-0691.2008.02095.x Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Area under the receiver operating characteristic curves (ROC AUC) for testing the ability of the LC Q-PCR to distinguish active from inactive brucellosis. ROC curves were constructed by plotting sensitivity and 1-specificity corresponding to each cut-off value for the Brucella DNA load. (a) Considering a cut-off of 5 × 103 copies/mL. (b) Considering a cut-off of 2.2 × 105 copies/mL to achieve a specificity of 100%. Clinical Microbiology and Infection 2008 14, 1128-1134DOI: (10.1111/j.1469-0691.2008.02095.x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions