Figure 1. Colony morphology of an A. fumigatus non-WT strain and an A

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Presentation transcript:

Figure 1. Colony morphology of an A. fumigatus non-WT strain and an A Figure 1. Colony morphology of an A. fumigatus non-WT strain and an A. fumigatus SC WT strain on caspofungin-containing ... Figure 1. Colony morphology of an A. fumigatus non-WT strain and an A. fumigatus SC WT strain on caspofungin-containing (2 mg/L) and drug-free agar after 24 and 48 h of incubation. Note the fluffy versus compact appearance. This figure appears in colour in the online version of JAC and in black and white in the print version of JAC. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) J Antimicrob Chemother, dkz154, https://doi.org/10.1093/jac/dkz154 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 2. Colony morphology of selected echinocandin WT A Figure 2. Colony morphology of selected echinocandin WT A. fumigatus SC and non-WT A. fumigatus isolates on agar ... Figure 2. Colony morphology of selected echinocandin WT A. fumigatus SC and non-WT A. fumigatus isolates on agar containing increasing effective concentrations (mg/L) of each echinocandin and drug-free agar (GC) in four-well plates after 24 and 48 h of incubation at 35 ± 2°C. This figure appears in colour in the online version of JAC and in black and white in the print version of JAC. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) J Antimicrob Chemother, dkz154, https://doi.org/10.1093/jac/dkz154 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 3. Agar-based screening method for three Aspergillus spp Figure 3. Agar-based screening method for three Aspergillus spp. in four-well plates containing increasing ... Figure 3. Agar-based screening method for three Aspergillus spp. in four-well plates containing increasing concentrations (mg/L) of echinocandins and drug-free agar (GC) after incubation at 35 ± 2°C for 24 h. This figure appears in colour in the online version of JAC and in black and white in the print version of JAC. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) J Antimicrob Chemother, dkz154, https://doi.org/10.1093/jac/dkz154 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 4. Production of an irregular (top left photograph) or a small (colony diameter ≤8 mm) (top right photograph) ... Figure 4. Production of an irregular (top left photograph) or a small (colony diameter ≤8 mm) (top right photograph) halo around A. niger SC and A. terreus SC WT isolates after incubation at 35 ± 2°C for 48 h. The morphology of colonies is clearly different from strains grown on drug-free agar with and without conidiogenesis (colony diameter ≥15 mm) (bottom photographs). This figure appears in colour in the online version of JAC and in black and white in the print version of JAC. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) J Antimicrob Chemother, dkz154, https://doi.org/10.1093/jac/dkz154 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 5. Colony morphology of three A Figure 5. Colony morphology of three A. fumigatus non-WT isolates after 24 and 48 h of incubation in the four-well agar ... Figure 5. Colony morphology of three A. fumigatus non-WT isolates after 24 and 48 h of incubation in the four-well agar screening plates containing 1 mg/L caspofungin (CAS), 0.25 mg/L anidulafungin (ANI) and 0.125 mg/L micafungin (MIC) and no drug (GC). This figure appears in colour in the online version of JAC and in black and white in the print version of JAC. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) J Antimicrob Chemother, dkz154, https://doi.org/10.1093/jac/dkz154 The content of this slide may be subject to copyright: please see the slide notes for details.