Figure 1. Time to clinical stability (a) and time to defervescence (b) in patients with pneumococcal pneumonia. ... Figure 1. Time to clinical stability.

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Figure 1. Time to clinical stability (a) and time to defervescence (b) in patients with pneumococcal pneumonia. ... Figure 1. Time to clinical stability (a) and time to defervescence (b) in patients with pneumococcal pneumonia. Kaplan–Meier curves for time to clinical stability and time to defervescence in patients with pneumococcal pneumonia treated with rifampicin versus patients treated without rifampicin. Filled circles, β-lactam without rifampicin; open circles, rifampicin with β-lactam. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com J Antimicrob Chemother, dkz207, https://doi.org/10.1093/jac/dkz207 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 2. Biomarkers in patients’ plasma before, during and after treatment. The inflammation biomarkers CRP, PCT and ... Figure 2. Biomarkers in patients’ plasma before, during and after treatment. The inflammation biomarkers CRP, PCT and MR-proADM were analysed in plasma. Median biomarker with IQR over time for patients with pneumococcal pneumonia (a–c) and for all patients (d–f). Filled circles, β-lactam without rifampicin; open circles, rifampicin with β-lactam. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com J Antimicrob Chemother, dkz207, https://doi.org/10.1093/jac/dkz207 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 3. Heatmap of RNA expression results measured by MLPA in all patients. Heatmap at time = 24 h for ... Figure 3. Heatmap of RNA expression results measured by MLPA in all patients. Heatmap at time = 24 h for rifampicin-treated patients (brown) versus patients treated without rifampicin (green). Clustering is poor for all genes investigated irrespective of clinical diagnosis. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com J Antimicrob Chemother, dkz207, https://doi.org/10.1093/jac/dkz207 The content of this slide may be subject to copyright: please see the slide notes for details.