Volume 59, Issue 4, Pages (April 2001)

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Volume 59, Issue 4, Pages 1473-1479 (April 2001) Effect of fluvastatin on endothelium-dependent brachial artery vasodilation in patients after renal transplantation Martin Hausberg, Markus Kosch, Frank Stam, Stefan Heidenreich, Klaus Kisters, Karl Heinz Rahn, Michael Barenbrock Kidney International Volume 59, Issue 4, Pages 1473-1479 (April 2001) DOI: 10.1046/j.1523-1755.2001.0590041473.x Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 1 Displayed are flow-mediated (FMD, left panel) and nitroglycerine-mediated vasodilation (NMD, right panel) of the brachial artery at baseline and after six months of treatment with fluvastatin (FLU; ▪) or placebo (PLA; □). Data are mean ± SEM. *P < 0.01 vs. baseline and P < 0.05 for group × time interaction. Kidney International 2001 59, 1473-1479DOI: (10.1046/j.1523-1755.2001.0590041473.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 2 Brachial artery distensibility coefficient (DC) at baseline and after six months of fluvastatin treatment (FLU; ▪) or placebo treatment (PLA; □). Data are mean ± SEM. Kidney International 2001 59, 1473-1479DOI: (10.1046/j.1523-1755.2001.0590041473.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 3 Change in brachial artery flow-mediated vasodilation (FMD) plotted against change in total serum cholesterol after six months of treatment with fluvastatin (FLU; ▪) or placebo (PLA; ○). Neither in FLU- nor in PLA-treated patients was there a significant correlation between the change in serum cholesterol and the change in FMD (r = 0.29, P = NS for FLU, and r = 0.16, P = NS for PLA). Kidney International 2001 59, 1473-1479DOI: (10.1046/j.1523-1755.2001.0590041473.x) Copyright © 2001 International Society of Nephrology Terms and Conditions