Activation of the coagulation system during coronary artery bypass grafting: Comparison between on-pump and off-pump techniques Domenico Paparella, MD,

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Presentation transcript:

Activation of the coagulation system during coronary artery bypass grafting: Comparison between on-pump and off-pump techniques Domenico Paparella, MD, Antonella Galeone, MD, Maria Teresa Venneri, BSc, Maria Coviello, BSc, Giuseppe Scrascia, MD, Nicola Marraudino, MD, Michele Quaranta, MD, Luigi de Luca Tupputi Schinosa, MD, Stephanie J. Brister, MD The Journal of Thoracic and Cardiovascular Surgery Volume 131, Issue 2, Pages 290-297 (February 2006) DOI: 10.1016/j.jtcvs.2005.10.018 Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Tissue factor (TF) values after log transformation and correction for hemodilution in 7 observation times. B, Prothrombin fragments 1.2 (PF 1.2) values after log transformation and correction for hemodilution in 7 observation times. Open squares, On-pump group; filled circles, OPCAB group. Significant P values obtained with the t test are reported. The Journal of Thoracic and Cardiovascular Surgery 2006 131, 290-297DOI: (10.1016/j.jtcvs.2005.10.018) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 A, Tissue plasminogen activator (TPA) values after log transformation and correction for hemodilution in 7 observation times. B, Plasminogen activator inhibitor-1 (PAI-1) values after log transformation and correction for hemodilution in 7 observation times. Open squares, On-pump group; filled circles, OPCAB group. Significant P values obtained with the t test are reported. The Journal of Thoracic and Cardiovascular Surgery 2006 131, 290-297DOI: (10.1016/j.jtcvs.2005.10.018) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 A, D-dimer (D-D) values after log transformation and correction for hemodilution in 7 observation times. B, Platelet function evaluated by the platelet function analyser-100 (PFA-100) after log transformation in 7 observation times. Two-way ANOVA for repeated measures: P <.0001. Open squares, On-pump group; filled circles, OPCAB group. Significant P values obtained with the t test are reported. The Journal of Thoracic and Cardiovascular Surgery 2006 131, 290-297DOI: (10.1016/j.jtcvs.2005.10.018) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions