Volume 95, Issue 4, Pages 724-726 (April 2019) Journal Club Kidney International Volume 95, Issue 4, Pages 724-726 (April 2019) DOI: 10.1016/j.kint.2019.02.006 Copyright © 2019 Terms and Conditions
Figure 1 A pathway-level map reveals specific targets of glucocorticoid action on individual cell types. (a) Pathways (rows) affected by glucocorticoid treatment of specific cell types (columns) arranged in modules of similar cell-type specificity. (b) Transcriptional effects of glucocorticoids on genes involved in B-cell receptor (BCR) signaling. (c) Transcriptional effects of glucocorticoids on genes involved in Toll-like receptor (TLR) signaling. Reprinted from Franco LM, Gadkari M, Howe KN, et al. Immune regulation by glucocorticoids can be linked to cell type–dependent transcriptional responses. J Exp Med. 2019;216: 384–406. Copyright © 2019 Franco et al. https://doi.org/10.1084/jem.20180595. ECM, extracellular matrix; GC, glucocorticoid, NFκB, nuclear factor kappa B. Kidney International 2019 95, 724-726DOI: (10.1016/j.kint.2019.02.006) Copyright © 2019 Terms and Conditions