Luís Henrique W. Gowdak, MD, PhD, Isolmar T

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Presentation transcript:

Cell Therapy Plus Transmyocardial Laser Revascularization for Refractory Angina Luís Henrique W. Gowdak, MD, PhD, Isolmar T. Schettert, MD, Carlos Eduardo Rochitte, MD, PhD, Luiz Augusto F. Lisboa, MD, PhD, Luís Alberto O. Dallan, MD, PhD, Luiz Antônio M. César, MD, PhD, José Eduardo Krieger, MD, PhD, José Antônio F. Ramires, MD, PhD, Sérgio A. de Oliveira, MD, PhD The Annals of Thoracic Surgery Volume 80, Issue 2, Pages 712-714 (August 2005) DOI: 10.1016/j.athoracsur.2005.04.080 Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Left ventricle short-axis images of first-pass perfusion during dipyridamole stress at baseline (upper left) and at 6 months after transmyocardial laser revascularization plus stem-cell therapy (lower left). Arrows (upper left) indicate an almost circumferential, subendocardial dark rim compatible with myocardial ischemia, which is not seen at follow-up (lower left). Myocardial delayed enhanced images (upper/lower right) revealed an anteroseptal myocardial infarction (arrow) equally seen in both exams. The Annals of Thoracic Surgery 2005 80, 712-714DOI: (10.1016/j.athoracsur.2005.04.080) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 End-systolic frame of left ventricle short-axis (left), 4-chamber (middle) and 2-chamber (right) views of cine magnetic resonance imaging are depicted at baseline (top) and at 6 months after the procedure (bottom). Arrows indicate the left ventricle mid anterior (left), basal anterior (middle), and anterolateral (right) segments that showed the most evident improvement in myocardial contractility defined by an increase in the end-systolic wall thickness at 6 months. Overall left ventricular functional improvement was mainly due to an increase in stroke volume (B = 48 mL versus 6 months = 77 mL), and a decrease in end-systolic volume (B = 129 mL versus 6 months = 101 mL), since there was no change in end-diastolic volume (B = 177 mL versus 6 months = 178 mL). The Annals of Thoracic Surgery 2005 80, 712-714DOI: (10.1016/j.athoracsur.2005.04.080) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions