The Lancet Child & Adolescent Health Association between fat mass through adolescence and arterial stiffness: a population- based study from The Avon Longitudinal Study of Parents and Children  Frida Dangardt, MD, Marietta Charakida, MD, Georgios Georgiopoulos, MD, Scott T Chiesa, PhD, Alicja Rapala, MA, Kaitlin H Wade, PhD, Prof Alun D Hughes, MB ChB, Prof Nicholas J Timpson, PhD, Konstantinos Pateras, MSc, Prof Nick Finer, MB ChB, Prof Naveed Sattar, MB ChB, Prof George Davey Smith, MD, Prof Debbie A Lawlor, MB ChB, Prof John E Deanfield, MB ChB  The Lancet Child & Adolescent Health  DOI: 10.1016/S2352-4642(19)30105-1 Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure PWV per combinations of metabolic health and adiposity status at 9 and 17 years of age Metabolically healthy includes all participants categorised as metabolically healthy at both 9 and 17 years of age, whereas metabolically unhealthy includes all participants categorised as metabolically unhealthy at either 9 or 17 years of age. The reference category comprised children who had normal fat mass and were metabolically healthy across adolescence. p values for linear trend are derived from multivariable regression analysis for PWV at 17 years adjusted for sex, height, socioeconomic status, systolic blood pressure, C-reactive protein, LDL, Z score of BMI, and birthweight. BMI=body-mass index. LDL=low-density lipoprotein. PWV=pulse wave velocity. *Significant difference (p<0·05) from the reference category. The Lancet Child & Adolescent Health DOI: (10.1016/S2352-4642(19)30105-1) Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions