Viral Suppressors of RNA-Based Viral Immunity: Host Targets

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Viral Suppressors of RNA-Based Viral Immunity: Host Targets Qingfa Wu, Xianbing Wang, Shou-Wei Ding  Cell Host & Microbe  Volume 8, Issue 1, Pages 12-15 (July 2010) DOI: 10.1016/j.chom.2010.06.009 Copyright © 2010 Elsevier Inc. Terms and Conditions

Figure 1 Mechanisms in the Viral Suppression of RNA-Based Viral Immunity VSRs target RNA and protein components of the RNA silencing pathway and inhibit siRNA production (B2, P6), RISC assembly (P0 and possibly P38), slicing activity of mature RISC (P1, 1A), amplification of viral secondary siRNAs (2b, RNaseIII (R3), V2), or intercellular movement of viral siRNAs (P19). Cell Host & Microbe 2010 8, 12-15DOI: (10.1016/j.chom.2010.06.009) Copyright © 2010 Elsevier Inc. Terms and Conditions