Volume 95, Issue 4, Pages (April 2019)

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Volume 95, Issue 4, Pages 896-904 (April 2019) Impact of estimation versus direct measurement of predonation glomerular filtration rate on the eligibility of potential living kidney donors François Gaillard, Marie Courbebaisse, Nassim Kamar, Lionel Rostaing, Lola Jacquemont, Maryvonne Hourmant, Arnaud Del Bello, Lionel Couzi, Pierre Merville, Paolo Malvezzi, Benedicte Janbon, Bruno Moulin, Nicolas Maillard, Laurence Dubourg, Sandrine Lemoine, Cyril Garrouste, Hans Pottel, Christophe Legendre, Pierre Delanaye, Christophe Mariat Kidney International Volume 95, Issue 4, Pages 896-904 (April 2019) DOI: 10.1016/j.kint.2018.11.029 Copyright © 2019 International Society of Nephrology Terms and Conditions

Figure 1 Relationship between eGFR (CKD-EPI equation, left; FAS equation, right) and mGFR in 2733 potential donors. Black dots represent misclassified individuals according to an absolute GFR threshold of 90 ml/min per 1.73 m2 (upper graphs) or 60 ml/min per 1.73 m2 (lower graphs). Kidney International 2019 95, 896-904DOI: (10.1016/j.kint.2018.11.029) Copyright © 2019 International Society of Nephrology Terms and Conditions

Figure 2 Misclassification of ineligible donors: eGFR of potential donors with a low mGFR for age among 2733 potential donors. Black dots represent individuals with abnormally low mGFR for age. (a) Relationship between age and mGFR. (b–e) Relationship between age and GFR estimated by 4 equations. Solid blue line represents the lower limit of GFR normality for age. Kidney International 2019 95, 896-904DOI: (10.1016/j.kint.2018.11.029) Copyright © 2019 International Society of Nephrology Terms and Conditions

Figure 3 Misclassification of eligible donors: mGFR of potential donors with a low eGFR for age among 2733 potential donors. Black dots represent potential donors with abnormally low eGFR for age. Relationship between age and mGFR (right column) or eGFR (left column) given by (a) the MDRD equation, (b) the CKD-EPI equation, (c) the FAS equation, and (d) the LM equation. Solid blue line represents the lower limit of normal GFR for age. Kidney International 2019 95, 896-904DOI: (10.1016/j.kint.2018.11.029) Copyright © 2019 International Society of Nephrology Terms and Conditions