The Structure of Host-Pathogen Interactions   Cell  Volume 157, Issue 3, (April 2014) DOI: 10.1016/j.cell.2014.04.012 Copyright © 2014 Terms and Conditions

RNase L forms a homodimer, which assembles a dimeric active site RNase L forms a homodimer, which assembles a dimeric active site. IRE1 uses similar sequence rules with RNase L for substrate cleavage. Image courtesy of A. Korennykh. Cell 2014 157, DOI: (10.1016/j.cell.2014.04.012) Copyright © 2014 Terms and Conditions

Upon antigen binding, IgG molecules organize in hexameric ring structures, which form docking stations for avid C1q binding that triggers the complement cascade. Image courtesy of P. Parren and J. Bakker (Scicomvisuals). Cell 2014 157, DOI: (10.1016/j.cell.2014.04.012) Copyright © 2014 Terms and Conditions

Cε2 domains display extreme flexibility from the bent (in violet/blue) to the extended structure (in red), relative to the Cε3 and Cε4 domains. Image courtesy of N. Drinkwater and B. Sutton. Cell 2014 157, DOI: (10.1016/j.cell.2014.04.012) Copyright © 2014 Terms and Conditions

Structure of the OspG/UbcH5c∼Ub complex with ATP modeled into the kinase active site. Image courtesy of P. Brzovic. Cell 2014 157, DOI: (10.1016/j.cell.2014.04.012) Copyright © 2014 Terms and Conditions