Volume 69, Issue 5, Pages (March 2006)

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Date of download: 7/9/2016 Copyright © The American College of Cardiology. All rights reserved. From: Local Renal Delivery of a Natriuretic Peptide: A.

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Volume 69, Issue 5, Pages 864-868 (March 2006) Selective endothelin B receptor blockade does not influence BNP-induced natriuresis in man K. van der Zander, A.J.H. M. Houben, D.J. Webb, E. Udo, B. Kietselaer, L. Hofstra, J.G.R. De Mey, P.W. de Leeuw Kidney International Volume 69, Issue 5, Pages 864-868 (March 2006) DOI: 10.1038/sj.ki.5000215 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Renal responses of sodium excretion (Na+, a), urinary volume (b), glomerular filtration rate (GFR, c), and effective renal plasma flow (ERPF, d) to intravenous infusion of placebo or BNP infusion with or without co-infusion of BQ-788. Data are presented as median and interquartile ranges. *P<0.05 versus baseline. #P<0.05 between interventions. Kidney International 2006 69, 864-868DOI: (10.1038/sj.ki.5000215) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 2 Supine mean arterial blood pressure (MAP, a) and heart rate (HR, b) at baseline and following 1 h infusion of placebo or BNP with or without co-infusion of BQ-788 for 15 min. Data are presented as median and interquartile ranges. *P<0.05 versus baseline. Kidney International 2006 69, 864-868DOI: (10.1038/sj.ki.5000215) Copyright © 2006 International Society of Nephrology Terms and Conditions