Common skin infection due to Panton–Valentine leucocidin-producing Staphylococcus aureus strains in asylum seekers from Eritrea: a genome-based investigation of a suspected outbreak L. Jaton, T. Pillonel, K. Jaton, E. Dory, G. Prod'hom, D.S. Blanc, F. Tissot, P. Bodenmann, G. Greub Clinical Microbiology and Infection Volume 22, Issue 8, Pages 739.e5-739.e8 (August 2016) DOI: 10.1016/j.cmi.2016.05.026 Copyright © 2016 The Author(s) Terms and Conditions
Fig. 1 (a) Phylogenetic tree of the 15 Panton–Valentine leucocidin (PVL) -positive strains isolated in Lausanne together with 35 publicly available Staphylococcus aureus genomes. Two clusters of eight CC152 and three ST15 PVL-producing strains could be identified. (b) Staphylococcus aureus toxin genes [16] identified in the 15 investigated strains: the two subunits of the PVL (lukF/S-PV), the exfoliative toxins a and b (eta/etb), the enterotoxins a b and c (sea/seb/sec) and the enterotoxin gene cluster (ecg: seg, sei, selm, seln, selo, selu). Presence of the toxins in other reference strains is indicated in blue. Numbers indicate the percentage of amino acid identity with the reference toxin (accession numbers are given in the Supplementary material, Table S3). Core genome-encoded toxins and toxins that were not found in any of the 15 genomes are reported in the Supplementary material (Figure S2). Clinical Microbiology and Infection 2016 22, 739.e5-739.e8DOI: (10.1016/j.cmi.2016.05.026) Copyright © 2016 The Author(s) Terms and Conditions