Supplementary Table S2 Correlation between pre-operative plasma miR-451 or miR-486 concentrations and clinicopathologic features in gastric cancer patients.

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Supplementary Table S2 Correlation between pre-operative plasma miR-451 or miR-486 concentrations and clinicopathologic features in gastric cancer patients N Mir-451 a P Mir-486 a Sex Male 31 9.03 (2.87-12.36) 0.26 (0.11-0.38) Female 25 4.16 (2.66-10.34) 0.181 0.25 (0.13-0.49) 0.315 Age (y) median 　　66　(35-87)　 <60 15 8.88 (2.72-12.45) 0.28 (0.19-0.33) 60≦ 41 6.09 (2.74-11.06) 0.265 0.22 (0.10-0.49) 0.248 Tumor size (cm) <5 29 9.03 (2.66-13.63) 0.28 (0.14-0.39) 5≦ 27 5.17 (2.80-9.78) 0.168 0.22 (0.11-0.44) 0.316 Histological type Well 34 8.53 (2.72-12.46) 0.30 (0.13-0.47) Poor 22 5.43 (2.77-10.23) 0.276 0.21 (0.12-0.37) 0.321 lymphatic invasion b - 28 9.46 (4.15-13.64) 0.30 (0.15-0.38) + 24 5.03 (2.42-10.28) 0.039 0.23 (0.08-0.56) 0.318 venous invasion b 8.04 (2.66-13.63) 0.28 (0.15-0.39) 6.09 (2.96-11.42) 0.262 0.26 (0.10-0.50) 0.356 pT stage m, sm 21 9.89 (3.08-13.63) 0.31(0.16-0.57) Others 35 5.17 (2.70-10.52) 0.100 0.19 (0.11-0.41) 0.127 pN stage 9.96 (3.80-13.34) 0.30 (0.16-0.57) 5.03 (2.66-10.63) 0.053 0.21 (0.11-0.44) 0.234 pTMN stage Ⅰ+Ⅱ 33 9.03 (4.15-13.63) 0.31 (0.14-0.43) Ⅲ+Ⅳ 23 3.86 (2.53-9.29) 0.016 0.19 (0.08-0.38) 0.135 recurrence b,c 8.04 (3.47-13.05) 0.32 (0.14-0.56) 12 7.02 (2.98-11.33) 0.341 0.23 (0.12-0.33) 0.129 residual tumor 47 8.04 (3.04-12.45) 0.31 (0.14-0.46) 9 2.74 (1.70-4.89) 0.011 0.10 (0.07-0.22) 0.018 a: Median of concentration (amol/μl) (with 25th-75th percentile) b: 4 cases could not be resected　 c: 5 cases with residual tumor after operation