Volume 68, Issue 5, Pages 1063-1075 (May 2018) Fructose and sugar: A major mediator of non-alcoholic fatty liver disease  Thomas Jensen, Manal F. Abdelmalek, Shelby Sullivan, Kristen J. Nadeau, Melanie Green, Carlos Roncal, Takahiko Nakagawa, Masanari Kuwabara, Yuka Sato, Duk-Hee Kang, Dean R. Tolan, Laura G. Sanchez-Lozada, Hugo R. Rosen, Miguel A. Lanaspa, Anna Mae Diehl, Richard J. Johnson  Journal of Hepatology  Volume 68, Issue 5, Pages 1063-1075 (May 2018) DOI: 10.1016/j.jhep.2018.01.019 Copyright © 2018 European Association for the Study of the Liver Terms and Conditions

Fig. 1 Association of added sugar consumption with rates of NAFLD, obesity in NHANES data. NAFLD, non-alcoholic fatty liver disease; NHANES, National Health and Nutrition Examination Survey. Journal of Hepatology 2018 68, 1063-1075DOI: (10.1016/j.jhep.2018.01.019) Copyright © 2018 European Association for the Study of the Liver Terms and Conditions

Fig. 2 Interaction of fructose, glucose and polyol pathway with uric acid and triglycerides. Journal of Hepatology 2018 68, 1063-1075DOI: (10.1016/j.jhep.2018.01.019) Copyright © 2018 European Association for the Study of the Liver Terms and Conditions

Fig. 3 Fructose mechanism mediating development and progression of NAFLD. DNL, de novo lipogenesis; ER, endoplasmic reticulum; KHK-C, ketohexokinase-C; NAFLD, non-alcoholic fatty liver disease. Journal of Hepatology 2018 68, 1063-1075DOI: (10.1016/j.jhep.2018.01.019) Copyright © 2018 European Association for the Study of the Liver Terms and Conditions