A Strategy for Determining Which Thoracic Esophageal Cancer Patients Should Undergo Cervical Lymph Node Dissection Shiro Nagatani, MD, Yutaka Shimada,

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A Strategy for Determining Which Thoracic Esophageal Cancer Patients Should Undergo Cervical Lymph Node Dissection Shiro Nagatani, MD, Yutaka Shimada, MD, PhD, Masato Kondo, MD, Junichi Kaganoi, MD, PhD, Masato Maeda, MD, PhD, Go Watanabe, MD, PhD, Masayuki Imamura, MD, PhD The Annals of Thoracic Surgery Volume 80, Issue 5, Pages 1881-1886 (November 2005) DOI: 10.1016/j.athoracsur.2005.04.051 Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 The prospective study process. Group A patients underwent cervical lymph node (LN) dissection because they were diagnosed as having upper mediastinal LN metastasis by intraoperative diagnosis. Group B patients received cervical LN dissection with randomized selection. Group C patients did not receive cervical LN dissection with randomized selection. (ESCC = esophageal squamous cell carcinoma.) The Annals of Thoracic Surgery 2005 80, 1881-1886DOI: (10.1016/j.athoracsur.2005.04.051) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Results of intraoperative detection of thoracic paratracheal lymph node (LN) metastasis and metastatic status in cervical lymph nodes. Cervical LN metastasis was detected by conventional hematoxylin and eosin staining and real-time reverse transcription-polymerase chain reaction. Cervical LN recurrence was followed up by commonly used diagnostic techniques, such as computed tomography and ultrasonography. The Annals of Thoracic Surgery 2005 80, 1881-1886DOI: (10.1016/j.athoracsur.2005.04.051) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan-Meier curves showing overall survival rate according to doing the neck dissection or not in 30 patients (log-rank test, p = 0.116). The Annals of Thoracic Surgery 2005 80, 1881-1886DOI: (10.1016/j.athoracsur.2005.04.051) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions