What’s the connection? Tetanus Typhoid Fever Whooping Cough Anthrax Pneumonia Salmonella Cholera Plague

Resistant Bacteria Self Manager Independent Enquirer Team Worker L.O: Understand what resistant bacteria are and how this links to the development of antibiotics and the theory of evolution. Grade 4: Describe what is meant by an antibiotic resistant bacteria, why scientists want to slow down the rate of development of new strains of antibiotic resistant bacteria and list some ways in which scientists can do this. Grade 6: Describe how antibiotic resistant bacteria evolve. Explain why scientists need to develop new antibiotics. Grade 8: Explain how a fast reproduction rate is linked to the development of antibiotic resistance strains of bacteria. Explain how antibiotic resistant bacteria are evidence for evolution. Summarise the reasons why the development of new antibiotics is unlikely to keep up with the emergence of new strains of antibiotic resistant bacteria. Self Manager Independent Enquirer Team Worker Effective Participator

How do we get antibiotic resistant bacteria? 2.4b Wipe out How do we get antibiotic resistant bacteria? Meet Paul. Paul’s throat is worse. He can hardly swallow. His doctor has given him an antibiotic. It will destroy the bacteria in his throat but it won’t cure his cold. Antibiotics don’t affect viruses. 3

2.4b Wipe out Paul’s doctor said, “Take every tablet even if you feel better soon.” Paul wonders why. 4

Meet the bacteria

It’s Paul’s first day on antibiotics… …and he already feels better

On the second day…. …he’s nearly cured.

On the third day…. …he feels great, so he stops taking his antibiotics.

On the fourth day…. …some bacteria are left….which could mutate.

And reproduce…..

Independent Enquirer Team Worker Effective Participator Task Complete the ‘News Report’ task in pairs – be prepared to show your news report to another group! H/w – exam qu or MRSA w/s saved? Independent Enquirer Team Worker Effective Participator

Peer Assessment WWW/EBI Give feedback in each student’s book using pink pen Have they included… Mutations produce new bacterial strains Antibiotic resistant bacteria are not killed by antibiotics They survive & reproduce so their population rises. The resistant strain spread as people are not immune and there is no effective treatment. We can reduce the rate of resistant bacteria by: Doctors only prescribing antibiotics for serious bacterial infections (i.e. not viruses/non serious infections) Patients completing their course of antibiotics Reducing the agricultural use of antibiotics. Development of new antibiotics is slow and costly. Unlikely to keep up with the emergence of new strains

How are antibiotic resistant bacteria evidence for evolution? THINK PAIR SHARE

Resistant Bacteria Self Manager Independent Enquirer Team Worker L.O: Understand what resistant bacteria are and how this links to the development of antibiotics and the theory of evolution. Grade 4: Describe what is meant by an antibiotic resistant bacteria, why scientists want to slow down the rate of development of new strains of antibiotic resistant bacteria and list some ways in which scientists can do this. Grade 6: Describe how antibiotic resistant bacteria evolve. Explain why scientists need to develop new antibiotics. Grade 8: Explain how a fast reproduction rate is linked to the development of antibiotic resistance strains of bacteria. Explain how antibiotic resistant bacteria are evidence for evolution. Summarise the reasons why the development of new antibiotics is unlikely to keep up with the emergence of new strains of antibiotic resistant bacteria. Self Manager Independent Enquirer Team Worker Effective Participator

Antibiotic resistance Stage 1: A person has a ___________ infection Stage 2- ___________ are used to kill the __________ causing the infection Stage 3- Some of the bacteria ___________ due to a random change in their DNA (a ___________) Stage 5- A new _______ of bacteria has ________ that is __________ to this particular antibiotic Stage 4- The ____________ bacteria ___________ quickly