Goal-Directed fluid therapy with closed-loop assistance during moderate risk surgery using noninvasive cardiac output monitoring: A pilot study  A. Joosten, T. Huynh, K. Suehiro, C. Canales, M. Cannesson, J. Rinehart  British Journal of Anaesthesia  Volume 114, Issue 6, Pages 886-892 (June 2015) DOI: 10.1093/bja/aev002 Copyright © 2015 The Author(s) Terms and Conditions

Fig 1 Graph of stroke volume, pulse pressure variation and fluid administration during a complicated case with major bleeding. This case was patient number 3. It was a redo of hip arthroplasty which was really complicated for the orthopedic surgeons. The surgical case was bleeding throughout the 5 h of the surgical case. The graph covers nearly the 5 h case during which 20 boluses of 100 ml (2000 ml) of albumin 5% was administered. As you can observed, shortly after induction, the closed-loop gives fluid until the stroke volume reaches the plateau of the Frank-Starling relationship and after delivers fluid to maintain the stroke volume constant during the case. British Journal of Anaesthesia 2015 114, 886-892DOI: (10.1093/bja/aev002) Copyright © 2015 The Author(s) Terms and Conditions