The efficacy, safety and carry-over effect of diacerein in the treatment of painful knee osteoarthritis: a randomised, double-blind, NSAID-controlled.

Slides:



Advertisements
Similar presentations
Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
Advertisements

The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis Ms L. Torres, B.A., Dr D.D. Dunlop, Ph.D., Dr C.
Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study 
NASHA hyaluronic acid vs methylprednisolone for knee osteoarthritis: a prospective, multi-centre, randomized, non-inferiority trial  R. Leighton, C. Åkermark,
Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis  Z. Huang, J. Chen, J. Ma, B. Shen,
Short-term placebo response in trials of patients with symptomatic osteoarthritis: differences between hip and knee  S. Reiter-Niesert, M. Boers, J. Detert 
Dr L. S. Kim, N. D. , Dr L. J. Axelrod, N. D. , Dr P. Howard, M. D
Efficacy and safety of naproxcinod in the treatment of patients with osteoarthritis of the knee: a 13-week prospective, randomized, multicenter study 
The epidemiology and impact of pain in osteoarthritis
P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung 
A. W. A. Baltzer, M. D. , C. Moser, M. D. , S. A. Jansen, M. D. , R
Effectiveness of chondroitin sulphate in patients with concomitant knee osteoarthritis and psoriasis: a randomized, double-blind, placebo-controlled study 
Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,
Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants 
Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role.
Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives  Y. Henrotin  Osteoarthritis and Cartilage 
Successful nonoperative management of chronic osteoarthritis pain of the knee: safety and efficacy of retreatment with intra-articular hyaluronans  Mark.
C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study  G. Engström, M.D., Ph.D.,
A multicenter, randomized controlled trial comparing a single intra-articular injection of Gel-200, a new cross-linked formulation of hyaluronic acid,
Pre-operative interventions (non-surgical and non-pharmacological) for patients with hip or knee osteoarthritis awaiting joint replacement surgery – a.
Transdermal buprenorphine plus oral paracetamol vs an oral codeine-paracetamol combination for osteoarthritis of hip and/or knee: a randomised trial 
Health-related quality of life and costs in patients with osteoarthritis on waiting list for total knee replacement  M. Núñez, Ph.D., E. Núñez, Ph.D.,
Efficacy and safety of intraarticular hyaluronic acid in the treatment of hip osteoarthritis: a systematic review  J.C. Fernández López, M.D., Ph.D.,
T. J. Schnitzer, N. E. Lane, C. Birbara, M. D. Smith, S. L. Simpson, M
A 3-month, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of a highly optimized, capacitively coupled, pulsed.
Time to be positive about negative data?
Equivalence of a single dose (1200 mg) compared to a three-time a day dose (400 mg) of chondroitin 4&6 sulfate in patients with knee osteoarthritis. Results.
Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,
Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee  H.R. Schumacher,
Efficacy of combined local mechanical vibrations, continuous passive motion and thermotherapy in the management of osteoarthritis of the knee  G.S. Kitay,
Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial  L.L.
J. Avouac, M.D., L. Gossec, M.D., M. Dougados, M.D. 
Decision aids for patients considering total joint replacement: a cost-effectiveness analysis alongside a randomised controlled trial  L. Trenaman, D.
S. Sonne-Holm, M.D., Dr. Sci., S. Jacobsen, M.D. 
Risk factors associated with reduced work productivity among people with chronic knee pain  M. Agaliotis, M. Fransen, L. Bridgett, L. Nairn, M. Votrubec,
Y.Y. Leung, J.L. Huebner, B. Haaland, S.B.S. Wong, V.B. Kraus 
Psychological factors and their relation to osteoarthritis pain
A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee 
N. Bodick, J. Lufkin, C. Willwerth, A. Kumar, J. Bolognese, C
Osteoarthritis year 2010 in review: non-pharmacologic therapy
Natural history of cartilage damage and osteoarthritis progression on magnetic resonance imaging in a population-based cohort with knee pain  J. Cibere,
Knee arthroscopic surgery is beneficial to middle-aged patients with meniscal symptoms: a prospective, randomised, single-blinded study  H. Gauffin, S.
Effectiveness of thermal and athermal short-wave diathermy for the management of knee osteoarthritis: a systematic review and meta-analysis  Y. Laufer,
Assessment of joint space narrowing with conventional standing antero-posterior radiographs: relief in mild-to-moderate pain is not a confounder in recent.
Efficacy and safety of duloxetine in Chinese patients with chronic pain due to osteoarthritis: a randomized, double-blind, placebo-controlled study  G.
The course of limitations in activities over 5 years in patients with knee and hip osteoarthritis with moderate functional limitations: risk factors for.
Total joint replacement after glucosamine sulphate treatment in knee osteoarthritis: results of a mean 8-year observation of patients from two previous.
Utilization rates of hip arthroplasty in OECD countries
A graphic user interface for the evaluation of knee osteoarthritis (GEKO): an open- source tool for histological grading  H.E. Kloefkorn, B.Y. Jacobs,
Preliminary results of a phase II randomized study to determine the efficacy and safety of genetically engineered allogeneic human chondrocytes expressing.
Who should have a joint replacement? A plea for more ‘phronesis’
Comparing two low-energy diets for the treatment of knee osteoarthritis symptoms in obese patients: a pragmatic randomized clinical trial  B.F. Riecke,
A single center, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy and safety of intra-articular onabotulinumtoxina as.
I.C. Olsen, T.K. Kvien, T. Uhlig  Osteoarthritis and Cartilage 
A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee  T.J. Schnitzer, J.A. Marks  Osteoarthritis.
D.J. Hunter  Osteoarthritis and Cartilage 
No additional benefit of shortwave diathermy over exercise program for knee osteoarthritis in peri-/post-menopausal women: an equivalence trial  M. Rattanachaiyanont,
Instruments to assess physical activity in patients with osteoarthritis of the hip or knee: a systematic review of measurement properties  C.B. Terwee,
C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec 
N. Frey, T. Hügle, S.S. Jick, C.R. Meier, J. Spoendlin 
Osteoarthritis year 2012 in review: biology
L.A. Deveza, L. Melo, T.P. Yamato, K. Mills, V. Ravi, D.J. Hunter 
T. Schäfer, F. Krummenauer, J. Mettelsiefen, S. Kirschner, K. P
Variations in pain and function before and after total knee arthroplasty: a comparison between Swedish and Australian cohorts  M.M. Dowsey, O. Robertsson,
Changes in pain, stiffness and physical function in patients with osteoarthritis waiting for hip or knee joint replacement surgery  H. Kapstad, R.N.,
M. Doherty, P. Dieppe  Osteoarthritis and Cartilage 
A randomised controlled trial of tidal irrigation vs corticosteroid injection in knee osteoarthritis: the KIVIS Study  N.K. Arden, M.D., I.C. Reading,
A new lipid formulation of low dose ibuprofen shows non-inferiority to high dose standard ibuprofen: the FLARE study (flaring arthralgia relief evaluation.
A. C. Lee, W. F. Harvey, L. L. Price, L. P. K. Morgan, N. L. Morgan, C
General Information Osteoarthritis and Cartilage
Presentation transcript:

The efficacy, safety and carry-over effect of diacerein in the treatment of painful knee osteoarthritis: a randomised, double-blind, NSAID-controlled study  W. Louthrenoo, M.D., S. Nilganuwong, M.D., S. Aksaranugraha, M.D., P. Asavatanabodee, M.D., S. Saengnipanthkul, M.D., the Thai Study Group  Osteoarthritis and Cartilage  Volume 15, Issue 6, Pages 605-614 (June 2007) DOI: 10.1016/j.joca.2007.02.021 Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Disposition of patients. Osteoarthritis and Cartilage 2007 15, 605-614DOI: (10.1016/j.joca.2007.02.021) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 WOMAC A – mean % change from baseline, SD (ITT population). Osteoarthritis and Cartilage 2007 15, 605-614DOI: (10.1016/j.joca.2007.02.021) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions