Figure 1. Genomic organization of the murine Pcln1 gene.

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Figure 1. Genomic organization of the murine Pcln1 gene. Figure 1. Genomic organization of the murine Pcln1 gene. The comparison with the human gene demonstrates highly conserved splice-sites. Human PCLN1 intron sizes were taken from two genomic clones (GenBank accession no. AC009520 and AC073963), which harbor PCLN1. Mouse Pcln1 intron sizes were calculated after PCR amplification and separation by agarose gel electrophoresis by applying a half-logarithmic function. Stefanie Weber et al. JASN 2001;12:2664-2672 ©2001 by American Society of Nephrology