Beneficial effects of ischemic preconditioning on right ventricular function after coronary artery bypass grafting Zhong-Kai Wu, MD, Matti R Tarkka, MD, Erkki Pehkonen, MD, Liisa Kaukinen, MD, Eva L Honkonen, MD, Seppo Kaukinen, MD The Annals of Thoracic Surgery Volume 70, Issue 5, Pages 1551-1557 (November 2000) DOI: 10.1016/S0003-4975(00)01850-6
Fig 1 Ischemic preconditioning (IP) protocol. (CPB = cardiopulmonary bypass; I = ischemia achieved by aortic cross clamping; min = minutes; R = reperfusion by releasing cross-clamping.) The Annals of Thoracic Surgery 2000 70, 1551-1557DOI: (10.1016/S0003-4975(00)01850-6)
Fig 2 Right ventricular function and global hemodynamics in patients who had coronary artery bypass grafting (CABG). (RVEF = right ventricular ejection fraction; RVSWI = right ventricular stroke work index; CI = cardiac index; LVSWI = left ventricular stroke work index; T0 = Baseline data before induction of anesthesia; T1 = 1 hour after declamping; T2 = 6 hours after declamping; T3 = first postoperative morning.) Data are presented as mean ± standard deviation. ∗p < 0.05, ∗∗p < 0.01. The Annals of Thoracic Surgery 2000 70, 1551-1557DOI: (10.1016/S0003-4975(00)01850-6)
Fig 3 Creatine kinase-MB (CK-MB) in patients who had coronary artery bypass grafting (CABG). (T1 = before cardiopulmonary bypass; T2 = after ischemic preconditioning (IP) or 10 minutes of cardiopulmonary bypass; T3 = 5 minutes after declamping; T4 = 6 hours after declamping; T5 = first postoperative morning; T6 = second postoperative morning.) Data are presented as mean ± standard deviation. The Annals of Thoracic Surgery 2000 70, 1551-1557DOI: (10.1016/S0003-4975(00)01850-6)