Vitamin K2 supplementation reduces dp-ucMGP but not dp-cMGP levels in dialysis patients. Vitamin K2 supplementation reduces dp-ucMGP but not dp-cMGP levels.

Slides:

Advertisements

Similar presentations

Among Medicare beneficiaries >65 years old with a index hospitalization at the time of dialysis initiation, use of post-acute SNF care was common. Among.

Advertisements

Patient disposition for the double-blind study period.

Positive interactions between the basic and translational research, clinical research, patient care, and training components of an academic dialysis access.

Histomorphology in a case of mixed (cellular and humoral) acute kidney allograft rejection (patient 10). Histomorphology in a case of mixed (cellular and.

Relationship between urinary TNF-α and RANTES excretion

Key amino acid positions identified by association analysis are highlighted in three-dimensional ribbon models for the HLA-DR, HLA-DQ, HLA-A and HLA-DP.

Five independent associations were identified after stepwise association analysis within the MHC region at the discovery stage. Five independent associations.

Differential expression of select miRNAs was validated in a second cohort of patients. Differential expression of select miRNAs was validated in a second.

Podocyte-specific PPAR-γ–deficient mice show increased glomerular TRPC6 expression. Podocyte-specific PPAR-γ–deficient mice show increased glomerular TRPC6.

Two independent amino acid positions were identified after stepwise association analysis for amino acids in HLA-DRβ1, HLA-DQα1 and HLA-DQβ1 in the combined.

Relationship between SBP levels and the urinary excretion of TNF-α (A), RANTES (B), and thiobarbituric acid–reacting substances (malondialdehyde [MDA];

Figure 2. Plasma lipoprotein cholesterol in apo-E −/− mice with CRF

Pedigrees of the families of patients 1 and 2 show that the clinical phenotype co-segregates with compound heterozygous CLDN10 variants. Pedigrees of the.

Figure 1. Plasma urea concentrations in apolipoprotein E–deficient (apo-E −/−) mice with chronic renal failure (CRF). Figure 1. Plasma urea concentrations.

Probability of cumulative incidence of ESRD, disease-related death, or death from other cause for the entire cohort. Probability of cumulative incidence.

Cytokine and chemokine expression of flucloxacillin-specific T cell clones (TCC) of patient P1. Cytokine and chemokine expression of flucloxacillin-specific.

Studies reporting the incident rate for all types of infections per 1000 patient days. Studies reporting the incident rate for all types of infections.

Figure 10. Recovery of the acetyl-CoA and ATP levels by glucose administration. Figure 10. Recovery of the acetyl-CoA and ATP levels by glucose administration.

Several microRNAs are differentially expressed in the glomeruli between different types of kidney disease. Several microRNAs are differentially expressed.

The proportion of DCD donor kidneys discarded was correlated with the proportion of NBD donor kidneys discarded within DSAs (Pearson correlation coefficient.

The incidence of all cause graft failure, and death with a functioning graft was higher in patients who received a DCD donor transplant with total donor.

Model of human CLC-Kb transporter topology and positions of amino acid exchanges due to mutations in the CLCNKB gene as identified in Bartter syndrome.

George A. Kaysen, Burl R. Don

Subgroup analysis. Subgroup analysis. Effect of vitamin D supplementation on outcome variables in subgroups defined by baseline levels of the respective.

Volume 70, Issue 7, Pages (October 2006)

Volume 67, Issue 1, Pages (January 2005)

Classification by HtTKV0 and age at HtTKV0 predicts the change in eGFR over time in class 1 patients. Classification by HtTKV0 and age at HtTKV0 predicts.

Trend of overall improvement in CKD risk categories after bariatric surgery using year 1 post-surgery as baseline. Trend of overall improvement in CKD.

Parathyroid hormone (PTH) levels by Dialysis Outcomes and Practice Patterns Study (DOPPS) phase and selected patient characteristics. Parathyroid hormone.

Volume 86, Issue 2, Pages (August 2014)

Patient disposition. Patient disposition. AE, adverse event. *One patient died during the follow-up period. ^Four of the 12 discontinuations of treatment.

(A through C) Mean eGFR during follow-up according to treatment assignment in patients with normoalbuminuria (A), microalbuminuria (B), and macroalbuminuria.

Urine ammonia is highly correlated with plasma K

Correcting hyperkalemia in DCT-CA-SPAK mice with a low K diet corrects differences in ammonia excretion and inducing hyperkalemia in WT mice, with the.

Thirty-day survival curves for the rapid versus slow correction rate groups are not significantly different. Thirty-day survival curves for the rapid versus.

Scatterplots showing the association between the three peritoneal equilibration test (PET) parameters. Scatterplots showing the association between the.

Changes in median exhaled CO levels from baseline to 12 weeks in quitters (n=183) and continuous smokers (n=94). Changes in median exhaled CO levels from.

Changes in St. George's Respiratory Questionnaire (SGRQ) scores from baseline to 12 weeks for total samples (n=277), quitters (n=183) and continuous smokers.

ILK knockdown increases the survival of PKD mice.

Hemodialysis patients represent a tiny subset of all patients with heart disease. Hemodialysis patients represent a tiny subset of all patients with heart.

The insulin tolerance test at week 18.

Box plots showing the relative difference in distribution of mtDNA copy number per cell between patients with ESRD and healthy control subjects frequency.

Representative photomicrographs of immunohistochemical staining for Wilms’ tumor 1 (WT1) and cleaved caspase-3 in mouse kidney sections at 10, 20, and.

(A) Mean (SD) serum continuous erythropoietin receptor activator (C. E

Lifestyle intervention was associated with improved cardiorespiratory fitness. Lifestyle intervention was associated with improved cardiorespiratory fitness.

Ionized-to-total magnesium (Mg) and calcium (Ca) ratios are lower in patients on hemodialysis than those in patients not on dialysis. Ionized-to-total.

Mean plasma concentrations of ampicillin/sulbactam in plasma of critically ill patients with AKI undergoing extended dialysis (duration depicted by box.

Dialyzer clearance of ampicillin/sulbactam in plasma of critically ill patients with AKI undergoing extended dialysis. Dialyzer clearance of ampicillin/sulbactam.

Ca2+ infusion rates during all three protocol versions.

Flow diagram illustrating diabetes outcomes in the randomly assigned treatment of folic acid and vitamins B6 and B12 of the WAFACS. A total of 1,190 participants.

Effect of randomized treatment on all renal events (top) and the composite of all renal events, macrovascular events, or all-cause mortality (bottom) according.

Rates of plasma sodium concentration increase before and after DDAVP administration. Rates of plasma sodium concentration increase before and after DDAVP.

Serum bicarbonate increased by ≥3, ≥4, and ≥5 mEq/L in 52%, 39%, and 22% of patients, respectively, in the combined TRC101 dose group compared with 6%,

Distribution of vascular access type (2002–2011) among countries with stable or decreasing catheter burden over time. Distribution of vascular access type.

Mortality caused by cardiovascular disease (A) and sepsis (B) of patients with end-stage renal disease (ESRD) treated by dialysis compared with the general.

Cumulative mortality risk in patients with 48-h blood urea nitrogen (BUN) levels of ≥8 mg/dl or

Gentamicin plasma and peritoneal dialysate concentrations in peritoneal dialysis patients with peritonitis. Gentamicin plasma and peritoneal dialysate.

Distribution of percent consistent facility aspirin use.

Changes in 44-hour interdialytic systolic BP as a function of change in echocardiographic volume parameter. Changes in 44-hour interdialytic systolic BP.

New dialysis starts in the United States by year in patients with and without diagnosis of diabetes. New dialysis starts in the United States by year in.

Separation in achieved BP levels between the two intervention groups in the SPRINT participants with CKD. The broken line and open circles denote the intensive.

As the patient nears the end of life (dashed arrow), there is an increasing focus on symptom control and patient goals of care and a shift in the approach.

Associations of dialysis session length with mortality and hospitalizations. Associations of dialysis session length with mortality and hospitalizations.

Renal hemodynamics. Renal hemodynamics. GFR (A), effective renal plasma flow (ERPF; B), and filtration fraction (FF; C) in patients with diabetes and with.

Prognostic algorithm. Prognostic algorithm. Although the temporal relationship between PLA2R Ab levels and disease activity is well established, a time.

Patient H: changes in circulating sFlt-1 levels and corresponding parameters after two apheresis treatments. Patient H: changes in circulating sFlt-1 levels.

Study design. aPatients initially receiving tenapanor 30 mg twice a day were allowed to down-titrate weekly (stepwise 30 → 20 → 15 → 10 → 3 mg twice a.

Study protocol. Study protocol. All participants were studied on four occasions: Twice before and twice after an 8-wk treatment period on low-dosage, low.

Mean number of dialysis sessions per patient for which intradialytic hypotension–related nursing interventions were required during the first 2 wk and.

Distribution of facility mean treatment time, by DOPPS region and phase. Distribution of facility mean treatment time, by DOPPS region and phase. Restricted.

Presentation transcript:

Vitamin K2 supplementation reduces dp-ucMGP but not dp-cMGP levels in dialysis patients. Vitamin K2 supplementation reduces dp-ucMGP but not dp-cMGP levels in dialysis patients. Plasma levels of dp-ucMGP and dp-cMGP at baseline and after 6 weeks of treatment with vitamin K2 (135 μg MK-7). (A) Changes in dp-ucMGP levels (**P < 0.01), whereas B depicts dp-cMGP levels (not significant) before (baseline) and after vitamin K2 substitution (vit K2), respectively. Georg Schlieper et al. JASN 2011;22:387-395 ©2011 by American Society of Nephrology