Predictive value of food sensitization and filaggrin mutations in children with eczema  Birgit Filipiak-Pittroff, MSc, Christina Schnopp, MD, Dietrich.

Slides:



Advertisements
Similar presentations
Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,
Advertisements

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,
Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,
Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.
Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007 Raymond James Mullins, MBBS, PhD, FRACP, FRCPA, Keith B.G.
Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor κB activation So Ri Kim, MD, PhD, Dong Im Kim, MS, Mi.
Infant-onset eczema in relation to mental health problems at age 10 years: Results from a prospective birth cohort study (German Infant Nutrition Intervention.
Joseph A. Odhiambo, MMed, Hywel C. Williams, PhD, Tadd O
The effect of hydrolyzed cow's milk formula for allergy prevention in the first year of life: The German Infant Nutritional Intervention Study, a randomized.
Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 
Longitudinal study on cat allergen exposure and the development of allergy in young children  Chih-Mei Chen, MSc, Peter Rzehak, PhD, Anne Zutavern, MD,
Is 9 more than 2 also in allergic airway inflammation?
Probiotics during the first 7 years of life: A cumulative risk reduction of eczema in a randomized, placebo-controlled trial  Marko Kalliomäki, MD, PhD,
Desensitization to Chemotherapeutic Agents
Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease  Elke Rodríguez, MSc, Hansjörg Baurecht, MSc, Esther.
Hansjörg Baurecht, MSc, Alan D
IgE sensitization in relation to preschool eczema and filaggrin mutation  Emma Kristin Johansson, MD, Anna Bergström, PhD, Inger Kull, RN, PhD, Tomas Lind,
Rising prevalence of asthma is sex-specific in a US farming population
Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J
Preventive effect of hydrolyzed infant formulas persists until age 6 years: Long-term results from the German Infant Nutritional Intervention Study (GINI) 
Allergy testing in predicting outcome of open food challenge to peanut
Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: International Study of Asthma and Allergies.
Physician needs in health informatics: Just ask the docs
Elder siblings enhance the effect of filaggrin mutations on childhood eczema: Results from the 2 birth cohort studies LISAplus and GINIplus  Claudia Cramer,
Peter M. Wolfgram, MD, David B. Allen, MD 
Etiology of asthma exacerbations
Childhood allergic rhinitis, traffic-related air pollution, and variability in the GSTP1, TNF, TLR2, and TLR4 genes: Results from the TAG Study  Elaine.
Joseph A. Odhiambo, MMed, Hywel C. Williams, PhD, Tadd O
Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA 
The prevalence of food allergy and other allergic diseases in early childhood in a population-based study: HealthNuts age 4-year follow-up  Rachel L.
An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma  Ingo Marenholz, PhD, Tamara Kerscher,
Intranasal triamcinolone use during pregnancy and the risk of adverse pregnancy outcomes  Anick Bérard, MSc, PhD, Odile Sheehy, MSc, Marie-Laure Kurzinger,
Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation  Leif Bjermer, MD  Journal of Allergy.
What are the best outcome measurements for atopic eczema
Is eczema really on the increase worldwide?
Anna Nowak-Wegrzyn, MD, Katherine A. Bloom, MD, Scott. H
Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management  Scott H. Sicherer, MD, Hugh A. Sampson, MD  Journal.
Biosimilars and drug development in allergic and immunologic diseases
Efficacy and safety of subcutaneous allergen-specific immunotherapy with depigmented polymerized mite extract in atopic dermatitis  Natalija Novak, MD,
Daphne Koinis-Mitchell, PhD, Timothy Craig, DO, Cynthia A
A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity  Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,
Association of NOD1 polymorphisms with atopic eczema and related phenotypes  Stephan Weidinger, MD, Norman Klopp, PhD, Lars Rummler, MD, Stefan Wagenpfeil,
What is an “eosinophilic phenotype” of asthma?
Onset of action of pimecrolimus cream 1% in the treatment of atopic eczema in infants  Roland Kaufmann, MD, Regina Fölster-Holst, MD, Peter Höger, MD,
H. William Kelly, PharmD  Journal of Allergy and Clinical Immunology 
Autophagy: Nobel Prize 2016 and allergy and asthma research
Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment
Advances in the approach to the patient with food allergy
Geographic variability in childhood asthma prevalence in Chicago
Mary F. Linehan, PhD, Timothy L. Frank, MD, Michelle L
A comprehensive analysis of the COL29A1 gene does not support a role in eczema  Aline Naumann, MSc, Cilla Söderhäll, PhD, Regina Fölster-Holst, MD, Hansjörg.
One step forward, 2 steps back: The enigma of preschool wheeze
Body mass index trajectory classes and incident asthma in childhood: Results from 8 European Birth Cohorts—a Global Allergy and Asthma European Network.
Susan A. Rudders, MD, Sarah A. Arias, PhD, Carlos A
Filaggrin mutations, atopic eczema, hay fever, and asthma in children
Acid-suppressive drug use in pregnancy and the toddler's asthma risk: A crossover, case-control study  Bianca Mulder, BSc, Catharina Carolina Maria Schuiling-Veninga,
Jessica H. Savage, MD, MHS, Elizabeth C. Matsui, MD, MHS, Robert A
Measles and immunomodulation
Atopic endotype in childhood
Macrolide antibiotics and asthma treatment
Asthma: The past, future, environment, and costs
Placental transfer of allergen-specific IgG but not IgE from a specific immunotherapy– treated mother  Sabine Flicker, PhD, Katharina Marth, MD, Heinz.
Environmental factors and eosinophilic esophagitis
Allergies in high-risk schoolchildren after early intervention with cow's milk protein hydrolysates: 10-year results from the German Infant Nutritional.
Advances in pediatric asthma in 2007
Natural history of cow’s milk allergy
In lasting tribute: Burton Zweiman, June 7, 1931–December 24, 2013
Primary prevention of asthma and allergy
Certain hydrolyzed formulas reduce the incidence of atopic dermatitis but not that of asthma: Three-year results of the German Infant Nutritional Intervention.
Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related.
Presentation transcript:

Predictive value of food sensitization and filaggrin mutations in children with eczema  Birgit Filipiak-Pittroff, MSc, Christina Schnopp, MD, Dietrich Berdel, MD, Aline Naumann, MSc, Simon Sedlmeier, Anna Onken, MD, Elke Rodriguez, MSc, Regina Fölster-Holst, MD, Hansjörg Baurecht, MSc, Markus Ollert, MD, Johannes Ring, MD, PhD, Claudia Cramer, MSc, Andrea von Berg, MD, Carl Peter Bauer, MD, Olf Herbarth, PhD, Irina Lehmann, PhD, Beate Schaaf, MD, Sibylle Koletzko, MD, Heinz-Erich Wichmann, MD, PhD, Joachim Heinrich, PhD, Stephan Weidinger, MD  Journal of Allergy and Clinical Immunology  Volume 128, Issue 6, Pages 1235-1241.e5 (December 2011) DOI: 10.1016/j.jaci.2011.09.014 Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 PPVs and NPVs (probability from 0 to 1) for the prediction of asthma at 7 to 10 years in children with early eczema for the prevalence of asthma (probability between 0 and 0.5) by different predictors. Journal of Allergy and Clinical Immunology 2011 128, 1235-1241.e5DOI: (10.1016/j.jaci.2011.09.014) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions