Mitochondrial genomes of extinct aurochs survive in domestic cattle

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Mitochondrial genomes of extinct aurochs survive in domestic cattle Alessandro Achilli, Anna Olivieri, Marco Pellecchia, Cristina Uboldi, Licia Colli, Nadia Al-Zahery, Matteo Accetturo, Maria Pala, Baharak Hooshiar Kashani, Ugo A. Perego, Vincenza Battaglia, Simona Fornarino, Javad Kalamati, Massoud Houshmand, Riccardo Negrini, Ornella Semino, Martin Richards, Vincent Macaulay, Luca Ferretti, Hans-Jürgen Bandelt, Paolo Ajmone-Marsan, Antonio Torroni  Current Biology  Volume 18, Issue 4, Pages R157-R158 (February 2008) DOI: 10.1016/j.cub.2008.01.019 Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 1 Tree of complete mtDNA sequences from cattle. This tree encompasses 56 novel sequences from Southern Europe and the Near East and 50 previously published sequences and was rooted by using a published Bos grunniens (yak) sequence and a novel Bison bison (American bison) sequence. Time estimates shown for clades and subclades are maximum likelihood (ML) estimates. However, the averaged distance (ρ) of the haplotypes of a clade to the respective root haplotype, accompanied by a heuristic estimate of standard error (σ) are also available in Supplemental data. BRS indicates the Bos taurus reference sequence [11]. The inset shows the reconstructed phylogeny based only on the coding-region sequence (from np 364 to np 15791) with an ML time scale shown on its left. Details concerning samples, mutational motifs of haplogroups and subhaplogroups as well as the protocol for sequencing entire mtDNAs are provided in Supplemental data. Current Biology 2008 18, R157-R158DOI: (10.1016/j.cub.2008.01.019) Copyright © 2008 Elsevier Ltd Terms and Conditions