Howard P. Greisler, M. D. , Eric D. Endean, M. D. , John J. Klosak, M

Slides:

Advertisements

Similar presentations

Shunya Shindo, M. D. , Atsuhiko Takagi, M. D. , Anthony D

Advertisements

Experimental study on a new tracheal prosthesis made from collagen-conjugated mesh Norihito Okumura, MD, Tatsuo Nakamura, MD, Tohru Natsume, MD, Kenji.

Age of onset, pattern of distribution, and histology of aneurysm development in a genetically predisposed mouse model Colleen M. Brophy, MD, Joan E.

Liposuction-derived human fat used for vascular graft sodding contains endothelial cells and not mesothelial cells as the major cell type Stuart K. Williams,

Mark F. Fillinger, MD, Emanuel R. Reinitz, MD, Robert A

Tissue soldering by use of indocyanine green dye-enhanced fibrinogen with the near infrared diode laser Mehmet C. Oz, MD, Jeffrey P. Johnson, BSE, Sareh.

Antisense oligonucleotide to proto-oncogene c-myb inhibits the formation of intimal hyperplasia in experimental vein grafts Gregory J. Fulton, MB, FRCSI,

Christopher K. Zarins, MD, Rodney A. White, MD, Thomas J. Fogarty, MD

Christopher K. Zarins, MD, Chengpei Xu, MD, Seymour Glagov, MD

Central venous catheter failure is induced by injury and can be prevented by stabilizing the catheter tip Ted R. Kohler, MD, Thomas R. Kirkman, BS Journal.

Infection of vascular prostheses caused by bacterial biofilms

Vascular anastomoses with laser energy

Development of a “leak-proof,” knitted Dacron vascular prosthesis

Prevention of perioperative vascular prosthetic infection with a novel triple antimicrobial- bonded arterial graft Ibrahim Aboshady, MD, Issam Raad, MD,

The role of circulating cells in the healing of vascular prostheses

Vida K. Stark, MS, Thomas F. Warner, MD, John R. Hoch, MD

An experimental study of eight current arterial prostheses

Christopher K. Zarins, MD, Rodney A. White, MD, Thomas J. Fogarty, MD

Phenotypic characterization of human smooth muscle cells derived from atherosclerotic tibial and peroneal arteries Bruce A. Jones, MD, Hamdy M. Aly,

Compound polyglactin 910/polypropylene small vessel prostheses

In situ localization and quantification of seventy-two – kilodalton type IV collagenase in aneurysmal, occlusive, and normal aorta William D. McMillan,

Long-term results of tissue development and cell differentiation on dacron prostheses seeded with microvascular cells in dogs Gabriela Baitella-Eberle,

Howard P. Greisler, MD, Joan Ellinger, Scott C. Henderson, Anne M

Dennis R. Holmes, MD, William Wester, BA, Robert W

Makoto Hashizume, M. D. , Ph. D. , Yeng Yang, M. D. , Spencer Galt, M

Mark F. Fillinger, MD, Susan E. O'Connor, MD, Robert J

An experimental study of eight current arterial prostheses

John Blebea, MD, John C. Kerr, BA, Charles D. Franco, MD, Frank T

Vincent L. Rowe, MD, Scott L. Stevens, MD, FACS, Tonya T

Michael A. Golden, MD, Y. P. Tina Au, PhD, Richard D

J. A. C. Buckels, M. D. , F. R. C. S. , A. G. Nordestgaard, M. D. , S

Malcolm O. Perry, MD, Richard Kempczinski, MD

Adventitial elastolysis is a primary event in aneurysm formation

Conformational stress and anastomotic hyperplasia

Randall Adolph, BS, David A. Vorp, PhD, David L. Steed, MD, Marshall W

Morphologic change in rabbit femoral arteries induced by storage at four degrees Celsius and by subsequent reperfusion Daniel Crowe, BSc(Hons), Kevin.

Hiromichi Miwa, MD, Takehisa Matsuda, PhD Journal of Vascular Surgery

Age of onset, pattern of distribution, and histology of aneurysm development in a genetically predisposed mouse model Colleen M. Brophy, MD, Joan E.

William W. Lin, BA, Gregory S. McGee, MD, Bruce K

Differences in reendothelialization after balloon catheter removal of endothelial cells, superficial endarterectomy, and deep endarterectomy Steven G.

In vitro construction of a human blood vessel from cultured vascular cells: A morphologic study Nicolas L'Heureux, MSc, Lucie Germain, PhD, Raymond Labbé,

Dacron inhibition of arterial regenerative activities

Paula K. Shireman, MD, Walter J. McCarthy, MD, William H

Rodney A. White, MD, Thomas J. Fogarty, MD, George E

Glenn C. Hunter, MD, Stephen H. Smyth, MD, Marie L. Aguirre, MD, B

Rapid cellular luminal coverage of Dacron inferior vena cava prostheses in dogs by immediate seeding of autogenous endothelial cells derived from omental.

John Blebea, MD, Robert A. Cambria, MD, David DeFouw, PhD, Richard N

Impact of endothelial cell seeding on long-term patency and subendothelial proliferation in a small-caliber highly porous polytetrafluoroethylene graft

True and false aneurysms in Behçet's disease: Case report with ultrastructural observations Antonio Freyrie, MD, Oreste Paragona, MD, Giovanna Cenacchi,

Primary leiomyosarcoma of the abdominal aorta

Inflammatory abdominal aortic aneurysms: A thirty-year review

Mostafa N. El-Sanadiki, MB, MS, K. Simon Cross, MB, John J

Effects of antiplatelet agents in combination with endothelial cell seeding on small- diameter Dacron vascular graft performance in the canine carotid.

Distal radial artery lesion as a source of digital emboli

Dog peritoneal and pleural cavities as bioreactors to grow autologous vascular grafts Wai-Leng Chue, MBBS, Gordon R Campbell, PhD, Noel Caplice, MBBS,

Endothelial cell harvest for seeding vascular prostheses: The influence of technique on cell function, viability, and number Bernard M. Bourke, M.B.B.S.,

Thrombus-free, human endothelial surface in the midregion of a Dacron vascular graft in the splanchnic venous circuit—Observations after nine months of.

Thoracoabdominal aortic aneurysm in Cogan’s syndrome

Differential effects of a gram-negative and a gram-positive infection on autogenous and prosthetic grafts Kevin J. Geary, MD, Zygmunt M. Tomkiewicz,

Prevention of perioperative vascular prosthetic infection with a novel triple antimicrobial- bonded arterial graft Ibrahim Aboshady, MD, Issam Raad, MD,

Aortic blebs: Possible site of aneurysm rupture

Richard L. Binns, MD Journal of Vascular Surgery

Endothelial cell seeding of a new PTFE vascular prosthesis

Phillip J. Cozzi, B. S. , Ross T. Lyon, M. D. , Harry R. Davis, Ph. D

Cells derived from omental fat tissue and used for seeding vascular prostheses are not endothelial in origin Michel J.T. Visser, MD, J.Hajo van Bockel,

Malignant fibrous histiocytoma of the aorta

William C. Quist, MD, PhD, Frank W. LoGerfo, MD

Michael A. Zatina, M. D. , Christopher K. Zarins, M. D. , Bruce L

James A. DeWeese, MD Journal of Vascular Surgery

Experimental study on a new tracheal prosthesis made from collagen-conjugated mesh Norihito Okumura, MD, Tatsuo Nakamura, MD, Tohru Natsume, MD, Kenji.

Presentation transcript:

Polyglactin 910/polydioxanone bicomponent totally resorbable vascular prostheses Howard P. Greisler, M.D., Eric D. Endean, M.D., John J. Klosak, M.D., Joan Ellinger, James W. Dennis, M.D., Karolyn Buttle, Dae Un Kim, M.D. Journal of Vascular Surgery Volume 7, Issue 5, Pages 697-705 (May 1988) DOI: 10.1016/0741-5214(88)90016-X Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Thickness (in microns) of inner capsule tissues as a function of time after implantation of 74% PG910/26% PDS prostheses, and 100% PG910 prostheses, and 100% PDS prostheses into white New Zealand white rabbit infrarenal aortas. Vertical lines indicate ± 1 SD. Journal of Vascular Surgery 1988 7, 697-705DOI: (10.1016/0741-5214(88)90016-X) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 A, One-month specimen shows PG910 inclusions (V) within macrophages and giant cell cytoplasm. The larger PDS filaments (P) are surrounded but not yet phagocytized by macrophages and giant cells. (Hematoxylineosin stain; original magnification × 550.) B, Transmission electron photomicrograph of midportion of specimen at 2 weeks shows various stages of PG910 inclusions (V) in the cytoplasm of either giant cells or macrophages. Cytoplasmic processes (arrows) are seen infiltrating into the substance of the PG910. (Original magnification × 7800.) Journal of Vascular Surgery 1988 7, 697-705DOI: (10.1016/0741-5214(88)90016-X) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 Midportion of PG910/PDS specimen at 2 months shows inner and outer capsules and residual prosthetic material consisting primarily of PDS (P). Inner capsule tissues are predominantly myofibroblasts and collagen beneath confluent endothelial-like luminal surface. (Hematoxylin-cosin stain; original magnification × 130.) Journal of Vascular Surgery 1988 7, 697-705DOI: (10.1016/0741-5214(88)90016-X) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Transmission electron photomicrograph of smooth muscle cell-like myofibroblast in inner capsule of 12-month specimen. Abundant myofilaments with dense bodies (arrows) are seen predominantly in peripheral regions of cytoplasm with marked attenuation of rough endoplasmic reticulum. (N = nucleus. Original magnification × 11,000.) Journal of Vascular Surgery 1988 7, 697-705DOI: (10.1016/0741-5214(88)90016-X) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Transmission electron photomicrograph of midportion of specimen at 12 months shows confluent luminal surface of endothelial cells with tight junctions and numerous pinocytotic vesicles on both apical and basal plasma membranes (original magnification × 7700). Insert, Higher magnification of boxed area shows near-transverse and near-longitudinal sections of rod-shaped microtubulated Weibel-Palade bodies (W-P with arrows) and pinocytotic vesicles (arrowheads). (Original magnification × 74,000.) Journal of Vascular Surgery 1988 7, 697-705DOI: (10.1016/0741-5214(88)90016-X) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 6 Scanning electron photomicrograph of midportion of specimen at 6 months shows confluent endothelial-like luminal surface. (Original magnification × 400.) Journal of Vascular Surgery 1988 7, 697-705DOI: (10.1016/0741-5214(88)90016-X) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 7 A, Production of 6-keto-PGF1α by luminal surface of each of six explanted prosthesistissue complexes measured as picograms produced per square millimeter of surface area, as function of time, perfused by culture media. After the 30-minute sampling, sodium arachidonate, 10 μg/ml, was added to the perfusate. The six specimens were explanted in duplicates at 24 hours (negative controls) and at 1 and 3 months. B, Production of 6-keto-PGF1α by normal control aortic segment of same six rabbits studied in A. Journal of Vascular Surgery 1988 7, 697-705DOI: (10.1016/0741-5214(88)90016-X) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions