The tetracycline-regulated female-killing system.

Slides:



Advertisements
Similar presentations
The need for gene regulation Bacterial genome4,000 genes Human genome100,000 genes Not all expressed at any one time May need very high levels e.g. translation.
Advertisements

Two ways to Regulate a Metabolic Pathway
Regulation of Gene Expression
Lecture 3: Models of gene regulation. DNA Replication RNA Protein TranscriptionTranslation.
20,000 GENES IN HUMAN GENOME; WHAT WOULD HAPPEN IF ALL THESE GENES WERE EXPRESSED IN EVERY CELL IN YOUR BODY? WHAT WOULD HAPPEN IF THEY WERE EXPRESSED.
Warm up Mon 11/3/14 Adv Bio 1. What does the phrase “gene regulation” mean? 2. If the lac operon cannot bind to the repressor.. What would be the outcome?
Control Mechanisms (Prokaryote) SBI4U. Controlling Expression  When a gene is being used by a cell, it gets transcribed, and then the mRNA is translated.
Control of Prokaryotic Gene Expression. Prokaryotic Regulation of Genes Regulating Biochemical Pathway for Tryptophan Synthesis. 1.Produce something that.
AP Biology Chapter 18: Gene Regulation. Regulation of Gene Expression Important for cellular control and differentiation. Understanding “expression” is.
Differentiation Cell & Molecular Biology. Genetic Control All cells in the body have the same genetic information Not all cells are identical. Cellular.
Four of the many different types of human cells: They all share the same genome. What makes them different?
Control of Gene Expression Big Idea 3: Living systems store, retrieve, transmit, and respond to info essential to life processes.
Microbial Genetics (Micr340) Lecture 15 Regulation of Gene Expression.
Antibiotics Bio February 2010 Ethan Richman Ben Kwak Ampicillin, Tetracyclin, and Chloramphenicol.
How Proteins are Made. I. Decoding the Information in DNA A. Gene – sequence of DNA nucleotides within section of a chromosome that contain instructions.
HIC1 attenuates Wnt signaling by recruitment TCF-4 and β-catenin to the nuclear bodies EMBO Journal (2006)
Control of gene expression Unit but different cells have different functions and look and act differently! WHY? Different sets of genes are expressed.
GENE REGULATION. Virtually every cell in your body contains a complete set of genes Virtually every cell in your body contains a complete set of genes.
Gene Expression and Regulation
Transposon “Jumping Genes” Insertion Sequence
Gene Regulation, Part 1 Lecture 15 Fall Metabolic Control in Bacteria Regulate enzymes already present –Feedback Inhibition –Fast response Control.
Gene Expression and Regulation
DNA Mutations Mutations are changes to the genetic information of the cell. There are 2 different types of mutations – Drives evolution – Most are silent.
GENE EXPRESSION. Pretty Please Back doorBig Brother.
KEY CONCEPT Gene expression is carefully regulated in both prokaryotic and eukaryotic cells. Chapter 11 – Gene Expression.
Chapter 13: Gene Regulation. The Big Picture… A cell contains more genes than it expresses at any given time – why? Why are cells in multicellular organisms.
Gene Expression & Regulation Chapter 8.6. KEY CONCEPT Gene expression is carefully regulated in both prokaryotic and eukaryotic cells.
Gene Expression Chapter 16. DNA regulatory sequence All on DNA Promoters – Start transcription Promoters – Start transcription Terminators – End Transcription.
The control of gene expression enable individual bacteria to adjust their meta- bolism to environmental change.
Warm Up Write down 5 times it would be beneficial for a gene to be ‘turned off’ and the protein not be expressed 1.
The lac Operon Laboratory Purpose: Learning to analyze an example of gene expression Example: lac operon Type of control: negative inducible.
Click to continue How do a few genes build a diversity of body parts? There’s more in the genetic toolkit than just genes! Click your forward cursor to.
Tet-Off® and Tet-On® Gene Expression Systems
Chapter 8, part B Microbial Genetics.
Chapter 8, part B Microbial Genetics.
Molecular Genetics: Part 2B Regulation of metabolic pathways:
Control of Gene Expression
Control of Gene Expression
Control of Gene Expression
Transcriptional Regulation
Regulation of Gene Expression
Daily Warm-Up Tuesday, Jan. 7th
Chapter 12.5 Gene Regulation.
Molecular Genetics Are we controlled by our DNA?
CONTROL MECHANISMS Sections 5.5 Page 255.
Auxin and GA promote fruit growth by activating ABA catabolism in the early stage and are important for the regulation of interlinked regulatory loops.
HSF1 in Translation Cancer Cell
How Proteins are Made.
Transcriptional response to mating in whole A. gambiae females.
Patterns of control of gene expression
Volume 74, Issue 4, Pages (August 2008)
Quiz#10 LC710 10/27/10 name___________
Gene Expression Activation of a gene to transcribe DNA into RNA.
The control of gene expression enable individual
Quiz#8 (8%) LC710 11/26/12 name___________
Volume 12, Issue 2, Pages (August 2005)
Non coding DNA Coding Not all DNA codes for a polypeptide to be made May have another useful function Non-coding sequences of DNA e.g. STRs Another example:
Chapter 18 Bacterial Regulation of Gene Expression
Prokaryotic (Bacterial) Gene Regulation
Volume 44, Issue 4, Pages (February 2018)
NsiR4 expression is mediated through an NtcA-activated promoter.
Chapter 8, part B Microbial Genetics.
Tissue-specific transcriptome responses to fasting.
Structure and receptor-binding properties of SCH-C.
Gene expression is reduced when RNAP binds a promoter too tightly.
Gene Regulation A gene (DNA) is expressed when it is made into a functional product (protein/enzyme)
Allen R. Buskirk, David R. Liu  Chemistry & Biology 
Engineering of D1- or D2-MSN-specific YCnano50 or ArchT-EGFP mice.
Opening Chromatin Molecular Cell
Presentation transcript:

The tetracycline-regulated female-killing system. The tetracycline-regulated female-killing system. Expression of tTA is controlled with the female- and fat-body-specific transcription enhancer from the yp1 gene (18). In the absence of tetracycline, tTA binds to tetO and induces expression of the proapoptotic gene hid. The loss of fat body results in female-specific lethality. In the presence of tetracycline, females are fully viable, because the binding of tTA to tetO is inhibited, switching off hid expression. Jörg C. Heinrich, and Maxwell J. Scott PNAS 2000;97:15:8229-8232 ©2000 by National Academy of Sciences

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.