S. pneumoniae GapA is sensitive to oxygen and H2O2 exposure.

Slides:

Advertisements

Similar presentations

A B C J K L CdFOMT1 CdFOMT3 CdFOMT4 CdFOMT5 1 kbp * * * *

Advertisements

Long-chain fatty acids are less abundant in the cecal contents of coconut oil-fed mice than in the cecal contents of beef tallow-fed mice. Long-chain fatty.

Chaperone Activity with a Redox Switch

Acid stability of the HA protein of clade

Trimeric association of TMDs of Ebola virus GP, SARS CoV S, rabies virus GP, and influenza virus HA, as determined by SE-AUC. Trimeric association of TMDs.

Chaperone Activity with a Redox Switch

Drawing Chemical Formulas Activity

Putative ammonia transporters are not required for ammonia release during N-acetylglucosamine pH neutralization. Putative ammonia transporters are not.

Effects of length-altering chemical treatments are more apparent after F-L synchronization. Effects of length-altering chemical treatments are more apparent.

Influence of K+ uptake on S. aureus metabolism.

Growth characteristics of strain 22A and its MDH mutant derivatives.

Observed (symbols) and model predicted (lines) dopamine time courses in rats following D-amphetamine administration. Observed (symbols) and model predicted.

5-ALA increased porphyrin production, which was further enhanced by vitamin B12 supplementation in acne-associated type IA-2 strains. 5-ALA increased porphyrin.

Volume 89, Issue 5, Pages (May 1997)

Sensor optimization for thiosulfate and tetrathionate detection in the gut Sensor optimization for thiosulfate and tetrathionate detection in the gut A–F(A.

Conditions that countered intracellular alkalization increased M

Comparison of the variable regions of (A) pHNZY32, pHNZY118, and pHNAH24; (B) pHNMCC14; (C) pHNFKU92; (D) pE80; (E) pECB11; (F) p42-2; and (G) pSLK172-2.

numbers letters colors shapes animals 1pt 1 pt 1 pt 1pt 1 pt 2 pt 2 pt

FepB is responsible for the smr mutant’s phenotype.

Quantification of drug cross-resistance between mutants selected for I-BET151 resistance and F0002 resistance. Quantification of drug cross-resistance.

Pearson correlation of gene expression identifies distinct groups of male- and female-enriched genes. Pearson correlation of gene expression identifies.

Inhibitory effect of T-705, ribavirin, T-1105, and T-1106 on SFTSV replication in Vero cells. Inhibitory effect of T-705, ribavirin, T-1105, and T-1106.

Outgrowth of passaged strains.

Quiescence of the E. coli CFT073 original clinical isolate on glucose plates. Quiescence of the E. coli CFT073 original clinical isolate on glucose plates.

The distribution of Sias in tissues from 10-day postfertilization embryonated chicken eggs. The distribution of Sias in tissues from 10-day postfertilization.

Gregory C. Adam, Benjamin F. Cravatt, Erik J. Sorensen*

Phylogenetic tree of K. variicola and K

Binding competition between B2′B3 and B3 fragments of TcdB.

The B2′B3 region confers the binding phenotype of full-length TcdB.

Microbial community structure analysis.

Maximum likelihood phylogeny of USA500 and other CC8 strains.

PVM candidates with a signal peptide and/or at least one transmembrane domain. PVM candidates with a signal peptide and/or at least one transmembrane domain.

Schematic illustration of polysaccharide capsule biosynthesis (A) and nucleotide/cofactor biosynthesis (B) in S. pneumoniae D39 and its relationship to.

Stress-protective roles of C. auris Hog1.

A model for SusG LES-mediated surface exposure and packing into OMV

RNA-Seq analysis of CYR1 cells in the adaptation to acid pH.

Activity of TP-271 administered i. v. and p. o

Dynamic ranges of anti-PnPS IgG Reference standard serum 007sp for each of 13 serotypes. Dynamic ranges of anti-PnPS IgG Reference standard serum 007sp.

Peel test of mucus–PCL adhesive strength.

Effect of pH and bicarbonate (HCO3) vs

Volume 10, Issue 4, Pages (October 2002)

Change in fluorescence of C. neoformans upon addition of DM262.

Prevention of quiescence by human urine and amino acids.

Gallium isotopes at m/z and 70

Phylogenetic tree of K. variicola from humans and animals.

Fibril-induced NM prions do not evolve from SGs.

Susceptibility to hydrogen peroxide.

Uptake of amino acids by C. albicans.

Fig. 3 Controlled phase shift.

Stress resistance comparisons.

MMEJ plays a dominant role in double-strand DNA break repair in L

Comparison of community fungal and bacterial/archaeal diversity levels

Distribution of the diversity numbers of antibiotic resistance and virulence factor protein families by environmental metagenomes’ protein family richness.

HPV–human protein network map.

Fig. 4 Relationships between light and economic parameters.

Mig1 influences the TOR and cell wall remodeling pathways.

PHs of olive brines. pHs of olive brines. The average ± standard deviation (SD) of two independent replicates at each time point is shown. Acetic acid.

Distribution of selected traits across the >4,000 strains in the most recent version of the database, including cell shape (A), spore formation (B), motility.

Fig. 5 Potential-energy energy profiles of 1-HAQ.

Pseudomonas PIV enhances pneumococcal pneumonia and bacteremia in C57BL/6 mice. Pseudomonas PIV enhances pneumococcal pneumonia and bacteremia in C57BL/6.

Primary screening results of the MMV Malaria Box library.

Water quality parameters.

Analysis of dCas9 expression.

Impact of the SOS activities on E. coli mutation rates.

LFO1 degrades heme to a distinct catabolite.

Prediction of cross-resistance among rifampin-resistant isolates.

PfHsp70x knockout does not inhibit export of PfEMP1 to the host cell.

Sensitivity and specificity of HbA1c, FPG, and 2hPG in identifying persons who developed diabetes within 10 years of screening among children and adolescents.

Presentation transcript:

S. pneumoniae GapA is sensitive to oxygen and H2O2 exposure. S. pneumoniae GapA is sensitive to oxygen and H2O2 exposure. (A) Specific activity of recombinant S. pneumoniae GapA at various pHs. (B) Specific activity of recombinant S. pneumoniae GapA after incubation with H2O2 (0 to 10 mM) at pH 7.0. (C) Specific activity of S. pneumoniae GapA highlighting the role of pH and H2O2 concentration. S. pneumoniae GapA is resistant to H2O2 at pH 6.0 (black circles). In the blue squares, the time-dependent inactivation of recombinant S. pneumoniae GapA is shown in the presence 0.3 mM H2O2 at pH 7.0. Green diamonds show time-dependent inactivation of recombinant S. pneumoniae GapA at pH 7.0 in the presence of 1 mM H2O2. Open symbols show the specific activity of S. pneumoniae GapA after incubation with DTT (50 mM). John P. Lisher et al. mSphere 2017; doi:10.1128/mSphere.00291-16