N. A. Guzzetta, F. Szlam, A. S. Kiser, J. D. Fernandez, A. D. Szlam, T

Slides:

Advertisements

Similar presentations

2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.

Advertisements

P.A. Bothma, C.J. Schlimp British Journal of Anaesthesia

J. W. Eikelboom, S. Kozek-Langenecker, A. Exadaktylos, A. Batorova, Z

Haemodilution-induced changes in coagulation and effects of haemostatic components under flow conditions† S. Ogawa, T. Ohnishi, K. Hosokawa, F. Szlam,

Human factors in anaesthesia: lessons from aviation

Reply from the authors British Journal of Anaesthesia

Haemodilution-induced profibrinolytic state is mitigated by fresh-frozen plasma: implications for early haemostatic intervention in massive haemorrhage

Recombinant activated factor VII and prothrombin complex concentrates have different effects on bleeding and arterial thrombosis in the haemodiluted rabbit

T. Tedore British Journal of Anaesthesia

Sevoflurane therapy for life-threatening asthma in children

Reduction in mortality after epidural anaesthesia and analgesia in patients undergoing rectal but not colonic cancer surgery: a retrospective analysis.

Characteristics of pain in hospitalized medical patients, surgical patients, and outpatients attending a pain management centre M.P. Rockett, G. Simpson,

Fluid responsiveness: an evolution of our understanding

Radioimmunoassay, enzyme and non-enzyme-based immunoassays

Type of anaesthesia and patient quality of recovery: a randomized trial comparing propofol–remifentanil total i.v. anaesthesia with desflurane anaesthesia

Changes in the effect of propofol in response to altered plasma protein binding during normothermic cardiopulmonary bypass E Takizawa, H Hiraoka, D Takizawa,

A different use of visual analytic techniques in anaesthetics

Perioperative factor concentrate therapy

J.C. Sleth, R. Servais, C. Saizy, W. Javitary, E. Lafforgue

Acupuncture for treatment of therapy-resistant post-dural puncture headache: a retrospective case series J. Dietzel, T. Witstruck, S. Adler, T.I. Usichenko

Inflating LMA with normal saline: 14 yr after

Effects of cardiopulmonary bypass on neurocognitive performance and cytokine release in old and diabetic rats F. de Lange, J.M. Dieleman, B. Jungwirth,

Ex vivo reversal of effects of rivaroxaban evaluated using thromboelastometry and thrombin generation assay B. Schenk, P. Würtinger, W. Streif, W. Sturm,

T Emerick, D Metro, R Patel, T Sakai British Journal of Anaesthesia

Effects of tirofiban on haemostatic activation in vitro†

Do team processes really have an effect on clinical performance

Differential diagnosis of facial pain and guidelines for management

Diastolic dysfunction, cardiopulmonary bypass, and atrial fibrillation after coronary artery bypass graft surgery C.M. Ashes, M. Yu, M. Meineri, R. Katznelson,

Comparison of the effects of albumin 5%, hydroxyethyl starch 130/0

Use of an anaesthesia workstation barrier device to decrease contamination in a simulated operating room S Hunter, D Katz, A Goldberg, H.-M. Lin, R Pasricha,

G.R. Lorello, D.A. Cook, R.L. Johnson, R. Brydges

Perioperative monitoring of platelet function in paediatric cardiac surgery by thromboelastometry, or platelet aggregometry?† B.S. Romlin, F Söderlund,

Anaesthesia for awake craniotomy—evolution of a technique that facilitates awake neurological testing A. Sarang, J. Dinsmore British Journal of Anaesthesia

Distraction and interruption in anaesthetic practice

U. Alström, L.-Å. Levin, E. Ståhle, R. Svedjeholm, Ö. Friberg

Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model F Kaspereit, S Hoffmann, I Pragst, G Dickneite

Β2-Adrenoceptor gene variants affect vasopressor requirements in patients after thoracic epidural anaesthesia U.H. Frey, J. Karlik, F. Herbstreit, J.

Anaesthetic staff cannot identify extremely high tracheal tube cuff pressures by palpation of the pilot balloon S.A. Michlig British Journal of Anaesthesia

Effects of oxytocin on Purkinje fibres

Recombinant activated factor VII for a patient with factor VII deficiency undergoing urgent intracerebral haematoma evacuation with underlying cavernous.

C. Price, J. Lee, A.M. Taylor, A.P. Baranowski

II. Should anaesthetists stop infusing isotonic saline?

Validation of a measurement tool for self-assessment of teamwork in intensive care J Weller, B Shulruf, J Torrie, R Frengley, M Boyd, A Paul, B Yee, P.

General anaesthesia with laryngeal mask airway may cause recurrence of pneumocephalus in a patient with head injury I Gurajala, M Azharuddin, R Gopinath

Z Mokini, C Buccino, G Vitale, T Mauri, R Fumagalli, A Pesenti

Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients: a systematic review R. Adams, G.T. Brown, M. Davidson,

Bone cement embolism attached to central venous catheter

Recovery of fibrinogen after administration of fibrinogen concentrate to patients with severe bleeding after cardiopulmonary bypass surgery C. Solomon,

Single-cuff forearm tourniquet in intravenous regional anaesthesia results in less pain and fewer sedation requirements than upper arm tourniquet† F.B.

Prothrombin complex concentrate vs fresh frozen plasma for reversal of dilutional coagulopathy in a porcine trauma model G. Dickneite, I. Pragst British.

Differential impacts of modes of anaesthesia on the risk of stroke among preeclamptic women who undergo Caesarean delivery: a population-based study

Effect of anaesthesia and cardiopulmonary bypass on blood endocannabinoid concentrations during cardiac surgery F Weis, A Beiras-Fernandez, D Hauer,

G.B. Drummond, B. Lafferty British Journal of Anaesthesia

Teamwork, communication, and anaesthetic assistance in Scotland

J Lee, S Gupta, C Price, A.P. Baranowski

Chronic widespread pain, including fibromyalgia: a pathway for care developed by the British Pain Society J. Lee, B. Ellis, C. Price, A.P. Baranowski

T. Kerforne, M. Chaillan, L. Geraud, O. Mimoz

R Hofmeyr, A Myburgh British Journal of Anaesthesia

New method of percutaneous radiofrequency mandibular nerve rhizotomy guided by high-speed real-time computed tomography fluoroscopy with direct approaching.

A.J. Ross, N. Kodate, J.E. Anderson, L. Thomas, P. Jaye

Pharmacological perioperative brain neuroprotection: a qualitative review of randomized clinical trials F. Bilotta, A.W. Gelb, E. Stazi, L. Titi, F.P.

IV. History of anaesthesia in Colombia: periods of development

Fraser D. Rubens, MD, MS, Gilbert Lavalee, Marc A

Cricoid pressure force retention analysis using a simulator

Reduced mortality by meeting guideline criteria before using recombinant activated factor VII in severe trauma patients with massive bleeding J.-F. Payen,

C.M. Chalmers, A.M. Bal British Journal of Anaesthesia

E. C. Hessian, B. E. Evans, J. A. Woods, D. J. Taylor, E Kinkel, A. R

Effect of concentration of local anaesthetic solution on the ED50 of bupivacaine for supraclavicular brachial plexus block† P.K. Gupta, P.M. Hopkins

R.L. Johnson, E.K. Cannon, C.B. Mantilla, D.A. Cook

R. Parke, S. McGuinness, R. Dixon, A. Jull

Presentation transcript:

Augmentation of thrombin generation in neonates undergoing cardiopulmonary bypass N.A. Guzzetta, F. Szlam, A.S. Kiser, J.D. Fernandez, A.D. Szlam, T. Leong, K.A. Tanaka British Journal of Anaesthesia Volume 112, Issue 2, Pages 319-327 (February 2014) DOI: 10.1093/bja/aet355 Copyright © 2014 The Author(s) Terms and Conditions

Fig. 1 Computer-simulated factor levels with and without added haemostatic agents. CPB, cardiopulmonary bypass; PCC, prothrombin complex concentrate; rFVIIa, recombinant activated factor VII. (a) Prothrombin levels; (b) Factor VII levels; (c) Factor X levels; (d) Antithrombin levels; x axis denotes time, y axis denotes concentration. British Journal of Anaesthesia 2014 112, 319-327DOI: (10.1093/bja/aet355) Copyright © 2014 The Author(s) Terms and Conditions

Fig. 2 Computer-simulated thrombin generation curves with and without added haemostatic agents. CPB, cardiopulmonary bypass; PCC, prothrombin complex concentrate; rFVIIa, activated recombinant factor VII; FII, factor II. British Journal of Anaesthesia 2014 112, 319-327DOI: (10.1093/bja/aet355) Copyright © 2014 The Author(s) Terms and Conditions