Increased severity and epidermal alterations in persistent versus evanescent skin lesions in adult-onset Still disease  Elina Zuelgaray, MD, Maxime Battistella, MD, PhD, Camille Sallé de Chou, MD, Marie-Dominique Vignon-Pennamen, MD, Michel Rybojad, MD, Antoine Petit, MD, Florence Cordoliani, MD, François Chasset, MD, Claude Bachmeyer, MD, Laurence Fardet, MD, PhD, Bruno Fautrel, MD, PhD, Patrice Cacoub, MD, PhD, Dan Lipsker, MD, PhD, Martine Bagot, MD, PhD, Jean-David Bouaziz, MD, PhD  Journal of the American Academy of Dermatology  Volume 79, Issue 5, Pages 969-971 (November 2018) DOI: 10.1016/j.jaad.2018.05.020 Copyright © 2018 Terms and Conditions

Fig 1 Atypical persistent skin eruptions (APSEs) in adult-onset Still disease (AOSD). A and B, A 58-year-old woman with AOSD who has pruritic, erythematous, and pigmented papules and plaques on the legs (A) and cheeks (B). C and D, A 46-year-old woman with AOSD who has moderate erythema on the metacarpophalangeal joints of the dorsal hands (C), erythema of the eyelids (D), and an erythematous plaque of the right leg. E, A 73-year-old man with AOSD who has lichenoid lesions on his legs. F, Skin biopsy of lichenoid lesions show epidermal alterations (necrotic keratinocytes, acanthosis, parakeratotic hyperkeratosis, and spongiosis) and an abundant neutrophilic perivascular and interstitial infiltrate. Journal of the American Academy of Dermatology 2018 79, 969-971DOI: (10.1016/j.jaad.2018.05.020) Copyright © 2018 Terms and Conditions