Standard Treatment: The Role of Antihistamines Hans F. Merk  Journal of Investigative Dermatology Symposium Proceedings  Volume 6, Issue 2, Pages 153-156 (November 2001) DOI: 10.1046/j.0022-202x.2001.00032.x Copyright © 2001 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 H1 receptores belong to the G-protein coupled receptor family. (Adapted fromChowdhury and Kaliner, 1996.) Journal of Investigative Dermatology Symposium Proceedings 2001 6, 153-156DOI: (10.1046/j.0022-202x.2001.00032.x) Copyright © 2001 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Antihistamines have a stronger effect on itching in urticaria than in other skin diseases such as atopic dermatitis. (Adapted fromHenz et al, 1998.) Journal of Investigative Dermatology Symposium Proceedings 2001 6, 153-156DOI: (10.1046/j.0022-202x.2001.00032.x) Copyright © 2001 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 3 In this PET analysis of H1-histamine receptors is the different effect by the nonsedating antihistamine terfenadine in comparison with the sedating antihistamine chlorpheniramine on CNS H1 receptors shown. (Adapted fromYanai et al, 1995.) Journal of Investigative Dermatology Symposium Proceedings 2001 6, 153-156DOI: (10.1046/j.0022-202x.2001.00032.x) Copyright © 2001 The Society for Investigative Dermatology, Inc Terms and Conditions