Peptide release is not impacted by phosphorothioate modification at interface of the P-site and A-site codons. Peptide release is not impacted by phosphorothioate.

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Peptide release is not impacted by phosphorothioate modification at interface of the P-site and A-site codons. Peptide release is not impacted by phosphorothioate modification at interface of the P-site and A-site codons. (A and B) Representative time courses for peptide release between the indicated initiation complexes (programmed with either a native mRNA or a racemic mixture of phosphorothioate mRNAs) and RF1 and RF2, respectively. Hannah E. Keedy et al. PNAS 2018;115:29:E6731-E6740 ©2018 by National Academy of Sciences