Clinical Comparisons in CTEPH
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) Background
CTEPH Definitions From the International Prospective CTEPH Registry
Medical Therapy Riociguat Mechanism of Action
CHEST-1 Study Design
CHEST-1 Riociguat for the Treatment of CTEPH
CHEST-1 Subgroup Analysis Inoperable and Postoperative Patients
CHEST-1 Safety Results
MERIT-1 Study Design
MERIT-1 Primary Endpoint Results
MERIT-1 Primary Endpoint by Subgroup
MERIT-1 Secondary Endpoint 6MWD
MERIT-1 Safety
Clinical Trials in CTEPH
Clinical Trials in CTEPH Hemodynamic Results
Clinical Trials in CTEPH Functional Capacity Results
CTEPH Is Not Just a Clot Problem
Microvasculopathy Associated With Proximal Disease in CTEPH
Small Vessel Disease May Be a Major Contributor to Persistent/Residual PH
Targeted Pharmacological Therapies for PAH and Possibly CTEPH
CTEPH Treatment Algorithm
Sequential Treatment With Riociguat and BPA in Patients With Inoperable CTEPH
Treatment Response to Multimodality Approach
CTEPH Trials in Progress
CTEPH Management
Conclusion
Abbreviations
Abbreviations (cont)