Trajectories of the Framingham general cardiovascular risk profile in midlife and poor motor function later in life: The Whitehall II study  Alexis Elbaz, Martin J. Shipley, Hermann Nabi, Eric J. Brunner, Mika Kivimaki, Archana Singh-Manoux  International Journal of Cardiology  Volume 172, Issue 1, Pages 96-102 (March 2014) DOI: 10.1016/j.ijcard.2013.12.051 Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Predicted trajectories of the Framingham general cardiovascular risk score from 1991–1993 to 2007–2009 by quartiles of motor tests assessed in 2007–2009. Graphs are based on the back transformation of the log-FRS predicted by linear mixed models (Table 4). Quartiles of walking speed, chair rises, finger tapping, and grip strength were defined based on age- and sex-specific distributions (supplementary Table 2): Q4 (best function), dotted line; Q3, short-dashed line; Q2, long-dashed line; Q1 (worst function), solid line. For balance (c): passed, dotted line; failed, solid line; this graph corresponds to men aged 65years in 2007–2009. Numbers on top of curves represent FRS differences between Q4 and Q1 (or between those who passed and failed the balance test) 16, 10, 5, and 0years before motor function was assessed (*p<0.05, †p<10−3). International Journal of Cardiology 2014 172, 96-102DOI: (10.1016/j.ijcard.2013.12.051) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions