High peripheral blood progenitor cell counts enable autologous backup before stem cell transplantation for malignant infantile osteopetrosis C.G. Steward,

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Presentation transcript:

High peripheral blood progenitor cell counts enable autologous backup before stem cell transplantation for malignant infantile osteopetrosis C.G. Steward, A. Blair, J. Moppett, E. Clarke, P. Virgo, A. Lankester, S.R. Burger, M.G. Sauer, A.M. Flanagan, D.H. Pamphilon, P.J. Orchard Biology of Blood and Marrow Transplantation Volume 11, Issue 2, Pages 115-121 (February 2005) DOI: 10.1016/j.bbmt.2004.11.001 Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Resolution of osteosclerosis after bone marrow transplantation. Before bone marrow transplantation (left), the leg bones were grossly sclerotic and showed flaring of the distal diaphyses (Ehrlenmeyer flask deformity). By 10 months after bone marrow transplantation (right), there was a marked reduction in bone density and an improvement in bone modeling. Biology of Blood and Marrow Transplantation 2005 11, 115-121DOI: (10.1016/j.bbmt.2004.11.001) Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions