Parvovirus B19: Assays, Limits and the Outcome Dr. Matthias Gessner Plasma Control/Plasma Analytics Baxter, Austria

1.8% 3

+ >50% pools to resolve

Conclusion A limit of 105 IU/ml on the production pool results in an actual limit of 104 IU/ml due to large CV of assays based on exponential amplification A limit of 105 IU/ml on the production pool results in an actual average load of 100 IU/ml (>90% of production pools <100 IU/ml) Lowering the limit to 104 IU/ml would put the actual limit to 103 IU/ml create 50% higher workload in resolving minipools avoid 1.8% of production pools in range of 103 IU/ml