Bronchioloalveolar Carcinoma Presenting as Chronic Progressive Pulmonary Infiltrates in a Woman with HIV: A Diagnosis Worth Making Todd M. Erickson,

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Presentation transcript:

Bronchioloalveolar Carcinoma Presenting as Chronic Progressive Pulmonary Infiltrates in a Woman with HIV: A Diagnosis Worth Making Todd M. Erickson, MD, John R. Koeppe, MD, York E. Miller, MD, Rodney W. Stuart, MD, D Ross Camidge, MD, PhD Journal of Thoracic Oncology Volume 3, Issue 11, Pages 1353-1355 (November 2008) DOI: 10.1097/JTO.0b013e31818b1ae1 Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 A, (H&E 200X) Bronchioloalveolar carcinoma within the transbronchial biopsy. Alveolar septa are lined by tall, columnar cells with mild nuclear pleomorphism and hyperchromasia, which project into spaces with papillary projections (arrow). The underlying lung architecture (right) is relatively preserved with thin vascular septa lined by benign pneumocytes. B, (H&E 400X) Bronchioloalveolar carcinoma within the transbronchial biopsy. The features of nuclear pleomorphism and hyperchromasia are better demonstrated on this high power view. Journal of Thoracic Oncology 2008 3, 1353-1355DOI: (10.1097/JTO.0b013e31818b1ae1) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Near complete response to therapy with erlotinib. Computed tomography (CT) chest at initiation of treatment with erlotinib (left) and after 6 months of therapy with erlotinib (right). Journal of Thoracic Oncology 2008 3, 1353-1355DOI: (10.1097/JTO.0b013e31818b1ae1) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions