Clustering of residues for which PREs unaccounted for by the main state were measured. Clustering of residues for which PREs unaccounted for by the main.

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Clustering of residues for which PREs unaccounted for by the main state were measured. Clustering of residues for which PREs unaccounted for by the main state were measured. The residues in green are those for which PREs were not measured or were successfully fitted by the main state; other residues are colored according to the clusters to which they belong. The solid spheres of a given color depict the geometric center of the corresponding cluster. (A) Probe 2 (PREs measured on Pdx): cluster A, red; cluster B, blue; and cluster C, orange. (B) Probe 3 (PREs measured on Pdx): cluster D, red; cluster E, blue; and cluster F, orange. (C) Probe 4 (PREs measured on cytP450cam): cluster G, red; cluster H, blue; and cluster I, orange. (D) Probe 6 (PREs measured on cytP450cam): cluster J, red; cluster K, blue; and cluster L, orange. CytP450cam orientation is the same as in Fig. 1. Witold Andrałojć et al. PNAS 2017;114:10:E1840-E1847 ©2017 by National Academy of Sciences