Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic.

Slides:

Advertisements

Similar presentations

Krinos M. Trokoudes, M. D. , Constantinos Pavlides, M. Sc

Advertisements

Demián Glujovsky, M.D., M.Sc., Cynthia Farquhar, M.D., M.P.H.

Successful pregnancy and delivery of two sets of monozygotic twins after intracytoplasmic sperm injection and embryo transfer: case report and literature.

Single blastocyst transfer: a prospective randomized trial

Outdoor air pollution and sperm quality

Sperm chromatin structure assay parameters are not related to fertilization rates, embryo quality, and pregnancy rates in in vitro fertilization and intracytoplasmic.

Taylor P. Kohn, M. Phil. , Jaden R. Kohn, B. S. , Alexander W

Randomized, controlled trial comparing the efficacy of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation.

Thyroid antibodies and gestational diabetes mellitus: a meta-analysis

Intrauterine injection of human chorionic gonadotropin before embryo transfer significantly improves the implantation and pregnancy rates in in vitro.

Clinical application of oocyte vitrification: a systematic review and meta-analysis of randomized controlled trials Ana Cobo, Ph.D., César Diaz, M.D.

Zhi-Yong Yang, M.D., Ri-Cheng Chian, Ph.D. Fertility and Sterility

Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study Nicole Hope, M.B., B.S., Hon., Luk.

Is frozen embryo transfer cycle associated with a significantly lower incidence of ectopic pregnancy? An analysis of more than 30,000 cycles Bo Huang,

A prospective randomized controlled trial of preimplantation genetic screening in the “good prognosis” patient Liza R. Meyer, M.S., Sigal Klipstein,

Eric J. Forman, M. D. , Kathleen H. Hong, M. D. , Kathleen M. Ferry, B

Cumulus cell transcriptome profiling is not predictive of live birth after in vitro fertilization: a paired analysis of euploid sibling blastocysts Katherine.

Examining the temperature of embryo culture in in vitro fertilization: a randomized controlled trial comparing traditional core temperature (37°C) to.

Live birth of twins derived from zona-free oocytes

Development and validation of an accurate quantitative real-time polymerase chain reaction–based assay for human blastocyst comprehensive chromosomal.

Increase of success rate for women undergoing embryo transfer by transcutaneous electrical acupoint stimulation: a prospective randomized placebo-controlled.

Does the addition of time-lapse morphokinetics in the selection of embryos for transfer improve pregnancy rates? A randomized controlled trial Linnea.

Surgical treatment of endometriosis: a prospective randomized double-blinded trial comparing excision and ablation Martin Healey, M.D., W. Catarina Ang,

Oocyte cryopreservation

Sequential versus Monophasic Media Impact Trial (SuMMIT): a paired randomized controlled trial comparing a sequential media system to a monophasic medium

Combination of uterine natural killer cell immunoglobulin receptor haplotype and trophoblastic HLA-C ligand influences the risk of pregnancy loss: a retrospective.

Oocyte cryopreservation outcomes including pre-cryopreservation and post-thaw meiotic spindle evaluation following slow cooling and vitrification of human.

Autologous mitochondrial transfer as a complementary technique to intracytoplasmic sperm injection to improve embryo quality in patients undergoing in.

I. Dimitriadis, G. Y. Christou, K. A. Dickinson, M. Thatcher, C. L

Initial IVF-ET experience with assisted hatching performed 3 days after retrieval followed by day 5 embryo transfer Margaret C. Graham, M.S., Kathleen.

Optimizing the culture environment and embryo manipulation to help maintain embryo developmental potential Jason E. Swain, Ph.D., Doug Carrell, Ph.D.,

Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded.

Use of testicular versus ejaculated sperm for intracytoplasmic sperm injection among men with cryptozoospermia: a meta-analysis Nikita Abhyankar, M.B.ChB.,

Single nucleotide polymorphism microarray–based concurrent screening of 24- chromosome aneuploidy and unbalanced translocations in preimplantation human.

High relative deoxyribonucleic acid content of trophectoderm biopsy adversely affects pregnancy outcomes Shelby A. Neal, M.D., Jason M. Franasiak, M.D.,

The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive.

Pretreatment with estrogen does not affect IVF-ICSI cycle outcome compared with no pretreatment in GnRH antagonist protocol: a prospective randomized.

Does intracytoplasmic sperm injection improve the fertilization rate and decrease the total fertilization failure rate in couples with well-defined unexplained.

Should embryos developing to blastocysts on day 7 be cryopreserved and transferred: an analysis of pregnancy and implantation rates George Kovalevsky,

Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical.

Age-specific probability of live birth with oocyte cryopreservation: an individual patient data meta-analysis Aylin Pelin Cil, M.D., Heejung Bang, Ph.D.,

Effect of semen quality on human sex ratio in in vitro fertilization and intracytoplasmic sperm injection: an analysis of 27,158 singleton infants born.

Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failure Elpida Fragouli, Ph.D., Mandy.

Electrical activation of oocytes after intracytoplasmic sperm injection: a controlled randomized study Ragaa Mansour, M.D., Ph.D., Ibrahim Fahmy, M.D.,

Ana Cobo, Ph. D. , Aila Coello, Ph. D. , Jose Remohí, M. D

Poor sperm quality affects clinical outcomes of intracytoplasmic sperm injection in fresh and subsequent frozen–thawed cycles: potential paternal effects.

Tong Du, M. S. , Hong Chen, M. D. , Rong Fu, M. S. , Qiuju Chen, Ph. D

Obesity does not impact implantation rates or pregnancy outcome in women attempting conception through oocyte donation Allison Styne-Gross, M.D., Karen.

Zsolt P. Nagy, M. D. , Ph. D. , Laura F. Rienzi, Ph. D. , Filippo M

Robust embryo identification using first polar body single nucleotide polymorphism microarray-based DNA fingerprinting Nathan R. Treff, Ph.D., Jing Su,

Single-blastomere whole-genome DNA fingerprinting results in unequivocal embryo identification – a powerful new clinical and diagnostic tool N.R. Treff,

Aneuploidy rate in donor oocyte cycles remain substantial, but are lower when compared to general infertility population J. Horne, J. Franasiak, M. Olcha,

L. Scott, J. Bernsten, K. DeLegge, J. Hill, N. Ramsing

Pregnancy loss in pregnancies conceived after in vitro oocyte maturation, conventional in vitro fertilization, and intracytoplasmic sperm injection William.

Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study Richard.

In Vitro Fertilization (IVF) Intracytoplasmic Sperm Injection (ICSI) Using Sperm Exposed to Cyclophosphamide Reduces Preimplantation Embryo Development.

Yoko Kumasako, B. E. , Eiko Otsu, M. En. , Takafumi Utsunomiya, M. D

Eric S. Surrey, M. D. , Debra A. Minjarez, M. D. , John M. Stevens, B

Assessing the reproductive competence of individual embryos: a proposal for the validation of new “-omics” technologies Richard T. Scott, M.D., H.C.L.D.,

Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery.

David H. Barad, M.D., M.S., Norbert Gleicher, M.D.

Day 3 morphology is a poor predictor of blastocyst quality in extended culture James Graham, M.S., Taer Han, B.S., Richard Porter, Michael Levy, M.D.,

Krinos M. Trokoudes, M. D. , Constantinos Pavlides, M. Sc

Are sperm DNA fragmentation, hyperactivation, and hyaluronan-binding ability predictive for fertilization and embryo development in in vitro fertilization.

Defining the “sweet spot” for administered luteinizing hormone-to-follicle-stimulating hormone gonadotropin ratios during ovarian stimulation to protect.

Comprehensive chromosome screening alters traditional morphology-based embryo selection: a prospective study of 100 consecutive cycles of planned fresh.

Effect of oocyte quality on blastocyst development after in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in a sheep model Maria.

Outcomes of vitrified early cleavage-stage and blastocyst-stage embryos in a cryopreservation program: evaluation of 3,150 warming cycles Ana Cobo, Ph.D.,

Nathan R. Treff, Ph. D. , Jessyca Campos, M. S. , Xin Tao, M. S

Male age negatively impacts embryo development and reproductive outcome in donor oocyte assisted reproductive technology cycles John L. Frattarelli,

Presentation transcript:

Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trial using DNA fingerprinting Eric J. Forman, M.D., Xinying Li, Ph.D., Kathleen M. Ferry, B.S., Katherine Scott, M.S., Nathan R. Treff, Ph.D., Richard T. Scott, M.D. Fertility and Sterility Volume 98, Issue 3, Pages 644-649 (September 2012) DOI: 10.1016/j.fertnstert.2012.04.028 Copyright © 2012 Terms and Conditions

Figure 1 Flow chart showing study enrollment and inclusion in study. Fertility and Sterility 2012 98, 644-649DOI: (10.1016/j.fertnstert.2012.04.028) Copyright © 2012 Terms and Conditions

Figure 2 Outcome of oocytes randomized to vitrification or control group demonstrates significantly lower fertilization, cleavage, and blastulation rates after vitrification. ∗P < .001. Fertility and Sterility 2012 98, 644-649DOI: (10.1016/j.fertnstert.2012.04.028) Copyright © 2012 Terms and Conditions

Figure 3 Equivalent aneuploidy rates among arrested embryos and usable blastocysts derived from previously vitrified and control oocytes. Fertility and Sterility 2012 98, 644-649DOI: (10.1016/j.fertnstert.2012.04.028) Copyright © 2012 Terms and Conditions